Samples of sputum were examined microscopically to determine their suitability for routine culture. When the number of squamous epithelial cells per field was less than 10, the number of bacterial species generally fell within the range of one to four. Squamous epithelial cells were not always a true indication because some unmarked transtracheal specimens showing more than 10 squamous epitheli...

We report five cases of duplicated external ear canal with especial attention to its histology and surgical care of facial nerve for their complete resection. These five patients were selected from 50 cases of first bronchial cleft anomalies including atretic external ear canals, preauricular fistula, cyst and sinuses. The characteristic histopathology and clinical features such as external ope...

AIM To study the differentiation of epithelial tissues within their histological context, and to identify hypothetically, on the basis of keratin pattern, the putative tissue origin of a (metastatic) carcinoma. METHODS Using well characterised monoclonal antibodies against individual keratins 7, 8, 18, and 19, which are predominantly found in columnar epithelia, and keratins 4, 10, 13, and 14...

Cutaneous immune-related adverse events (cirAEs) are the most common toxicities to occur in setting of immune checkpoint inhibitor (ICI) therapy. This multi-institutional retrospective cohort study examines relationship between cancer type, tumor tissue and cirAE development. Using data from Mass General Brigham Dana-Farber, we identified 3,711 ICI recipients, whom 672 developed cirAEs reviewed...

Background & Objective: Epithelial-Mesenchymal transition (EMT) is known to be a possible mechanism in tumor progression; however, there insufficient evidence support the contribution of this process human cancers. The present study aimed evaluate expression EMT markers normal oral epithelium and squamous cell carcinoma also correlates with some clinicopathological parameters.Methods: This was ...

we report five cases of duplicated external ear canal with especial attention to its histology and surgical care of facial nerve for their complete resection. these five patients were selected from 50 cases of first bronchial cleft anomalies including atretic external ear canals, preauricular fistula, cyst and sinuses. the characteristic histopathology and clinical features such as external ope...

Pleomorphic adenoma (PA) is the most common benign tumor of major salivary glands and intra nasal PA unusual which may be misdiagnosed as malignancy. A 65-year-old female presented with unilateral bleeding obstruction in right cavity for 6 months. Local examination showed polypoid mass surgically excised. HPE classic triphasic component epithelial, myoepithelial cartilaginous stromal elements p...

Mouse models can closely mimic human oral squamous epithelial carcinogenesis, greatly expand the in vivo research possibilities, and play a critical role in the development of diagnosis, monitoring, and treatment of head and neck squamous cell carcinoma. With the development of the recent research on the contribution of immunity/inflammation to cancer initiation and progression, mouse models ha...

BACKGROUND Epithelial neoplasms are uncommon lesions affecting the sino-nasal tract. There are hardly any reports in the Indian literature. AIM To study the incidence, mode of presentation and histological types of sino-nasal epithelial tumours in the surgical pathology material. SETTING AND DESIGN Retrospective retrieval of all sino-nasal tumours and analysis of epithelial tumours. MATER...

High risk human papillomaviruses are squamous epitheliotropic viruses that may cause cervical and other cancers. HPV replication depends on squamous epithelial differentiation. Transformation of HPV-infected cells goes along with substantial alteration of the viral gene expression profile and preferentially occurs at transformation zones usually at the uterine cervix. Methylation of the viral g...