نتایج جستجو برای: spreading depolarization

تعداد نتایج: 47219  

Journal: :The Journals of Gerontology Series A: Biological Sciences and Medical Sciences 2014

Ali Gorji , Jalil Arabkheradmand , Javad Mirnajafi-zade , Mahyar Janahmadi , Marius Alexander Eickhoff , Parviz Shahabi , Yaghoub Fathollahi ,

Introduction: A close link between spreading depression (SD) and several neurological diseases such as epilepsy could be demonstrated in many experimental studies. Epilepsy is among the most common brain disorders. Despite a large number of investigations, its mechanisms have not been yet well elucidated. Hippocampus is one of the important structures involved in seizures. The aim of this st...

2009
Jens P. Dreier Sebastian Major Andrew Manning Johannes Woitzik Chistoph Drenckhahn Jens Steinbrink Christos Tolias Ana I. Oliveira-Ferreira Martin Fabricius Jed A. Hartings Peter Vajkoczy Martin Lauritzen Ulrich Dirnagl Georg Bohner Anthony J. Strong

The term cortical spreading depolarization (CSD) describes a wave of mass neuronal depolarization associated with net influx of cations and water. Clusters of prolonged CSDs were measured time-locked to progressive ischaemic damage in human cortex. CSD induces tone alterations in resistance vessels, causing either transient hyperperfusion (physiological haemodynamic response) in healthy tissue;...

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