From the biochemical standpoint, perhaps the most striking effect of ionizing radiations on living systems involves a defect in the metabolism of the nucleic acids. Thus, one can cite a large number of observations in the literature (1, 18, 14, 16, @8) which state that the incorporation of a variety of labeled precursor substances (inorganic phos phate, formate, NaHCO5, glycine) into tissue des...

AIM This study's aimwas to determine the accuracy of the spleen stiffness value acquired using acoustic radiation force impulse (ARFI) technology, to predict the presence of esophageal varices (EVs) in patients with liver cirrhosis of various etiologies. MATERIAL AND METHODS Of the 366 enrolled patients, 192 had hepatitis B virus, 74 had hepatitis C virus, and 100 had alcohol-related cirrhosi...

postmortem examination of a 5.5-year-old holstein cow with history of sudden death showed a veryhuge spleen (120 × 45 × 10 cm) associated with severe haemoperitoneum. histopathological findingsincluded extensive infiltration of medium to large sized lymphocytic and lymphoblastic cells with smallamounts of cytoplasm, round nuclei with coarsely granular chromatin in the spleen, and limited foci o...

Backgrounds: It remains unclear whether radiation-induced haemorrhage in the spleen causes iron accumulation, and subsequently, ferroptosis in splenic lymphocytes. In this study, we investigated the occurrence of ferroptosis in splenic lymphocytes of gamma-irradiated mice. Materials and Methods: Mice were subjected to gamma radiation from a 137Cs source. Iron, Ferroportin 1, and iron regulatory...

AIM To verify whether curcumin (Cur) can treat inflammatory bowel disease by regulating CD8+CD11c+ cells. METHODS We evaluated the suppressive effect of Cur on CD8+CD11c+ cells in spleen and Peyer's patches (PPs) in colitis induced by trinitrobenzene sulfonic acid. Mice with colitis were treated by 200 mg/kg Cur for 7 d. On day 8, the therapeutic effect of Cur was evaluated by visual assessme...

Abstract Background and Aims Standard ultrasound mainly offers information about structural kidney alterations which may provide dates regarding the mass of filtrating (e.g. nephron number), or obstructive alterations. Furthermore, parenchymal Doppler resistance index, is highly correlated to plasma creatinine levels. However, in conditions isolated proteinuria with normal function these two cl...

OBJECTIVE To investigate the therapeutic effects and mechanism of Salvia miltiorrhizae in the treatment of SAP and OJ. METHODS A total of 288 rats were used for SAP- and OJ-associated experiments. The rats were randomly divided into sham-operated group, model control group and treated group. The mortality rates of rats, contents of endotoxin and PLA(2) in blood, pathological changes of differ...

OBJECTIVE It is known that the measurement of splenic length in routine clinical practice is a very good indicator of actual splenic size. Knowledge of the normal range of spleen size in the population being examined is a prerequisite. Racial differences in splenic length could result in incorrect interpretation of splenic measurements. The purpose of this study was to establish the range of sp...

discussion splenic artery aneurysm is a very uncommon cause of page kidney and to our knowledge, it was the first case of its kind ever reported in the literature. introduction the page kidney is a rare phenomenon that refers to hypertension resulting from any external compression of a kidney by a hematoma, tumor, lymphocele, or urinoma. the activation of the renin-angiotensin-aldosterone syste...