In this project transcriptome analysis on highthroughput RNA-sequencing (RNA-Seq) data of boar spermatozoa will be utilized to identify novel genetic markers associated with semen freezability. Three boars each with poor and good semen freezability will be subjected to transcriptome studies on sperm RNA-seq data, and in combination with bioinformatics screening, will select candidate genes asso...

In mouse and man Y chromosome deletions are frequently associated with spermatogenic defects. Mice with extensive deletions of non-pairing Y chromosome long arm (NPYq) are infertile and produce sperm with grossly misshapen heads, abnormal chromatin packaging and DNA damage. The NPYq-encoded multi-copy gene Sly controls the expression of sex chromosome genes after meiosis and Sly deficiency resu...

BACKGROUND This is the first study to assess the outcome of sperm washing and intrauterine insemination (IUI) cycles in human immunodeficiency virus-positive (HIV(+)) men to determine any predictors of success, as well as evaluating the effect of HIV on sperm parameters. METHODS Semen characteristics were evaluated in 106 HIV(+) men and a control group of 234 HIV(-) men, and the effect of mar...

Background and Aim: Reduction in sperm motility is one of the main causes of male infertility. The aim of this study was to investigate the effect of Carob supplementation on sperm parameters, inflammatory factors, oxidative stress indices and sex hormones in the men with idiopathic infertility. Materials and Methods: This study was a randomized double-blind controlled clinical trial which inc...

The 5th edition of WHO Laboratory Manual for the Examination and Processing of Human Semen (2010) represents a comprehensive revision. This article aims to explore the applicability of this manual to andrology laboratories in China mainland in view of sperm count analysis, sperm motility analysis, sperm morphology analysis, sperm function analysis, anti-sperm antibody and seminal plasma biochem...