Background: Obesity and increased body mass index (BMI) affect the reproductive parameters in men such as poor semen quality, decreased sperm concentration, decreased normal-motile sperm cells and increased DNA fragmentation index. Lipid peroxidation contributes to the damage of the sperm plasma membrane. The Curcuma Longa is a resource of antioxidants, hence in this study also was evaluated th...

background: one of the main laboratory tests for evaluation of infertility is semen analysis (sa). however additional tests may be suggested for further diagnosis of male fertility potentials. the seminal fluid contains sperms non-sperm cells and various types of lipids and glucose. objective: the objective of this cross-sectional study was to correlate the sperm parameters with concentrations ...

OBJECTIVE To determine the abnormal patterns of reactive oxygen species (ROS) production in male factor infertility (MFI) patients and to define the ROS reference values in such patients. DESIGN A retrospective study. SETTING Male infertility clinic at a tertiary healthcare center. PATIENT(S) We examined 132 MFI patients (all normal sperm parameters, n = 24, and all abnormal sperm paramet...

Semen analysis, sperm DNA fragmentation (SDF) and hypo-osmotic swelling test (HOST) are usually performed for the evaluation of sperm fertilizing ability. There are some debates over the necessity of SDF and HOST incorporation in male infertility work-up.Semen of 77 men was evaluated by SDF and HOST through three semen analyses. Sperm parameters were arranged into different categories: <5%, 5-1...

background: klc3 protein as a member of the kinesin light-chain protein family plays an important role in spermatogenesis, during formation of mitochondrial sheath in the mid piece of the sperm tail. objective: this study for the first time aims to compare the expression of the klc3 gene between fertile and infertile individuals. materials and methods: semen samples were collected from 19 ferti...

Background: Fertilization and fecundation obviously are the phenomenon in which several factors are involved. Sperm membranous proteins are a series of these important elements. CD9, an inner acrosomal membrane protein, is one of the tetraspanin members that involved in sperm-egg fusion. CD52, is a GPI anchor protein which is expressed in the epididymal cells and during passage of sperms throug...

Background Standardization of the semen analysis may improve reproducibility. We assessed variability between laboratories in semen analyses and evaluated whether a transformation using Z scores and regression statistics was able to reduce this variability. MaterialsAndMethods We performed a retrospective cohort study. We calculated between-laboratory coefficients of variation (CVB) for sperm c...