In single photon emission computed tomography (SPECT), accurate attenuation maps are needed to perform essential attenuation compensation for high quality radioactivity estimation. Formulating the SPECT activity and attenuation reconstruction tasks as coupled signal estimation and system parameter identification problems, where the activity distribution and the attenuation parameter are treated...

  Introduction: Monte Carlo (MC) is the most common method for simulating virtual SPECT projections. It is useful for optimizing procedures, evaluating correction algorithms and more recently image reconstruction as a forward projector in iterative algorithms; however, the main drawback of MC is its long run time. We introduced a model based method considering the eff...

introduction: monte carlo (mc) is the most common method for simulating virtual spect projections. it is useful for optimizing procedures, evaluating correction algorithms and more recently image reconstruction as a forward projector in iterative algorithms; however, the main drawback of mc is its long run time. we introduced a model based method considering the effect of body attenuation and i...

Monte Carlo algorithms have a growing impact on nuclear medicine reconstruction processes. One of the main limitations myocardial perfusion imaging (MPI) is effective mitigation scattering component, which particularly challenging in Single Photon Emission Computed Tomography (SPECT). In SPECT, no timing information can be retrieved to locate primary source photons. methods allow an event-by-ev...

BACKGROUND After yttrium-90 ((90)Y) microsphere radioembolization (RE), evaluation of extrahepatic activity and liver dosimetry is typically performed on (90)Y Bremsstrahlung SPECT images. Since these images demonstrate a low quantitative accuracy, (90)Y PET has been suggested as an alternative. The aim of this study is to quantitatively compare SPECT and state-of-the-art PET on the ability to ...

Quantitative measurement of myocardium perfusion is possible with single photon emission computed tomography (SPECT) using a semiconductor detector. However, accumulation of 99mTc-tetrofosmin in the liver may make it difficult to assess that accurately in the inferior myocardium. Our idea is to reduce the high accumulation in the liver by using dynamic SPECT imaging and a technique called time ...

Introduction: Quantitative evaluation is recommended to improve diagnostic ability and serial assessment of dopamine transporter (DAT) density scans. We decided to compare the ordered subsets expectation-maximization (OSEM) with filtered back-projection (FBP), and to investigate the impact of different iteration and cut-off frequencies on SBR values. Methods</stro...

objective: iqspect is an advanced high-speed spect modality for performing myocardial perfusion imaging (mpi), which uses a multi-focus fan beam collimator with resolution recovery reconstruction. the aim of this study was to compare iqspect compared with conventional spect interms of performance based on standard clinical protocols. in addition, we examined the concordance between conventional...