As with the advancement of geographical information systems, non-Gaussian spatial data sets are getting larger and more diverse. This study develops a general framework for fast flexible regression, especially spatial/spatiotemporal modeling. The developed model, termed compositionally-warped additive mixed model (CAMM), combines an (AMM) Gaussian process to wide variety continuous including ot...

Amelanotic malignant melanoma (AMM) is a subtype of cutaneous melanoma with little or no pigment upon visual inspection. The lack of pigmentation is the reason for late diagnosis of lesions and a poor prognosis. We report a case of a 55-year-old female with an AMM diagnosed by immunophenotyping. Monoclonal antibodies S-100, HMB-45, and antibodies to cytokeratin were used. Our patient underwent ...

Although human amniotic mesenchymal stem cells (AMMs) have been recognised as a promising stem cell resource, their therapeutic potential for wound healing has not been widely investigated. In this study, we evaluated the therapeutic potential of AMMs using a diabetic mouse wound model. Quantitative real-time PCR and ELISA results revealed that the angiogenic factors, IGF-1, EGF and IL-8 were m...

RATIONALE Amelanotic malignant melanoma (AMM) is a rare subtype of malignant melanoma (MM) that manifests atypically and is easily misdiagnosed or missed altogether. The keloid type of AMM has rarely been reported. Herein, we provide information to improve the clinical diagnosis of AMM types and raise awareness to ensure early diagnosis and timely treatment. PATIENT CONCERNS A 20-year old wom...

Current dogma favors elimination of therapy-resistant cancer stem cells for chemoprevention of breast cancer. We showed recently that mammary cancer development in a transgenic mouse model (mouse mammary tumor virus-neu; MMTV-neu) was inhibited significantly upon treatment with withaferin A (WA), a steroidal lactone derived from a medicinal plant. Herein, we demonstrate that the mammary cancer ...

We have studied the dynamics of finite N -unit FitzHugh-Nagumo (FN) ensembles subjected to additive and/or multiplicative noises, reformulating the augmented moment method (AMM) with the Fokker-Planck equation (FPE) method [H. Hasegawa, J. Phys. Soc. Jpn. 75, 033001 (2006)]. In the AMM, original 2N dimensional stochastic equations are transformed to eight-dimensional deterministic ones, and the...

Currently, Java has been gradually applied in embedded real-time areas like robotics, control system, etc. owning to its advantages like robustness, security, etc. In order to improve the performance of Java’s execution engine for embedded real-time applications, JPOR-32, an embedded real-time Java processor, is designed. Based on it, this paper presents the automatic memory management (AMM) me...

PURPOSE Anorectal malignant melanomas (AMM) are rare and have poor survival. The study aims to evaluate the clinicopathologic characteristics and outcomes of patients with AMM, and to devise a staging system predictive of survival outcome. MATERIALS AND METHODS This was a retrospective study of 28 patients diagnosed with, and treated for AMM. Patients classified by clinical staging of mucosal...

This study assessed the accuracy of a selected formula used to estimate the appendicular muscle mass (AMM) which is linked with many clinical outcomes. A group of community-dwelling adult women (n=80) had their AMM measured using dual energy x-ray absorptiometry (DXA). The same was estimated using a formula already published {Skeletal muscle mass = (0.244 × BW in kg) + (7.80 × Ht in meters) + (...

Traditionally, waterborne ammonia is considered a toxicant that decreases productivity in aquaculture. However, several recent studies have suggested, but not proven, that growth of salmonids might actually be stimulated by chronic exposure to very low levels of ammonia. In the present study, two 70-71 day growth experiments were conducted under rigorously controlled experimental conditions wit...