Microgravity, hypergravity, vibration, ionizing radiation and temperature fluctuations are major factors of outer space flight affecting human organs and tissues. There are several reports on the effect of space flight on different human cell types of mesenchymal origin while information regarding changes to vascular endothelial cells is scarce. Ultrastructural and cytophysiological features of...

Space flight and models that created conditions similar to those that occur during space flight have been shown to affect a variety of immunological responses. These have primarily been cell-mediated immune responses including leukocyte proliferation, cytokine production, and leukocyte subset distribution. The mechanisms and biomedical consequences of these changes remain to be established. Amo...

Results are given of biological experiments on space ship-satellites II, III, IV and V, and of scientific investigations made during the flights of Cosmonauts Gagarin and Titov aboard space ships Vostok I and Vostok II. Physiological reactions to the action of the flight stress-factors are not of a pathological character. In the post-flight period no alterations in health conditions of either c...

Modeling has been created for a " Space-to-Surface " system defined for an optimal trajectory for targeting in terminal phase with avoids an intercepting process. The modeling includes models for simulation atmosphere, speed of sound, aerodynamic flight and navigation by an infrared system. The modeling and simulation includes statistical analysis of the modeling results. Aerospace CyberResearc...

Midodrine prevents post-space flight orthostatic intolerance when testing is conducted in a controlled laboratory setting within 2-4 hours after Space Shuttle landing. It is unknown if midodrine is as effective during re-entry and immediately following landing. METHODS: Cardiovascular responses to 10 minutes of 80° head-up tilt in five male astronauts were compared before and immediately after ...