3,4-dihydropyrimidin-2(1h)-thiones were synthesized in the presence of ag nanoparticle/melamine sulfonic acid (msa) supported on silica gel. the reaction was carried out at 110 oc for 20 min under solvent free conditions. in all cases, the three component reaction proceeded smoothly to give the corresponding 3,4-dihydropyrimidin-2(1h)-thiones in moderate to good yield. we have found the best co...

Oxalic acid dihydrate as a green, mild and efficient catalyst for the one-pot three-component Biginelli synthesis of 3,4-dihydropyrimidin-2-(1H)-one derivatives from the reaction between β-keto esters (methyl or ethyl acetoacetate), aromatic aldehyde (benzaldehye derivatives) and urea or thiourea under thermal and solvent-free conditions with excellent yields and short reaction time is st...

1,8-dioxo-decahydroacridines have been synthesized by the three-component reaction of aromatic aldehydes, aromatic amines (or ammonium acetate), and dimedone in the presence of sulfonic acid functionalized nanoporous silica (sba-pr-so3h) under solvent-free conditions. excellent yields, short reaction times, mild reaction conditions, and easy work-up procedures are advantages of this green method.

Phthalocyanine complexes of Cu, Co, Ni, Fe, Zn, Pd, Pt and Ru have been synthesized from reaction between phthalonitrile and proper metal salts upon exposure to microwave irradiation under solvent-free conditions and considerably reduced reaction times.

A facile and efficient method for the preparation of 1,1-diacetates of aldehydes is improved. The acidified kaolin with sulfuric acid (2 % w/w) catalyzed 1,1-diacetates formation from aldehydes in solvent-free conditions. Both aromatic and aliphatic aldehydes gave high yields (85-95 %) of the corresponding 1, 1-diacetates. Advantages of this method are the use of inexpensive and selective catal...

3,4-dihydropyrimidin-2(1H)-thiones were synthesized in the presence of Ag nanoparticle/melamine sulfonic acid (MSA) supported on silica gel. The reaction was carried out at 110 oC for 20 min under solvent free conditions. In all cases, the three component reaction proceeded smoothly to give the corresponding 3,4-dihydropyrimidin-2(1H)-thiones in moderate to good yield. We have found the best co...

This work described an efficient Pseudo four-component synthesis of (10E)-N-benzylidene-2-phenylH-imidazo[1,2-a]pyridin-3-amine derivatives from 2-aminopyridin, malononitrile and arylaldehydes in the presence of NaOH under solvent-free and conventional heating condition in good to excellent yields. A wide range of aromatic aldehydes would easily undergo condensations with 2-aminopyridin and mal...

melamine trisulfonic acid (mtsa) is utilized as a highly efficient catalyst for the solvent-free condensation reaction of 2-naphthol (2 eq.) with arylaldehydes (1 eq.) under conventional thermal as well as microwave conditions to give the d

A facile and efficient method for the preparation of 1,1-diacetates of aldehydes is improved. The acidified kaolin with sulfuric acid (2 % w/w) catalyzed 1,1-diacetates formation from aldehydes in solvent-free conditions. Both aromatic and aliphatic aldehydes gave high yields (85-95 %) of the corresponding 1, 1-diacetates. Advantages of this method are the use of inexpensive and selective catal...

This work describes a fast, mild, convenient and simple method for preparing of nitrogen heterocyclic derivatives by MCR reaction under solvent-free condition.