This paper describes a fabrication protocol for a dipole-assisted solid phase extraction (SPE) microchip available for trace metal analysis in water samples. A brief overview of the evolution of chip-based SPE techniques is provided. This is followed by an introduction to specific polymeric materials and their role in SPE. To develop an innovative dipole-assisted SPE technique, a chlorine (Cl)-...

A polymeric microfluidic device for solid-phase extraction (SPE)-based isolation of nucleic acids is demonstrated. The plastic chip can function as a disposable sample preparation system for different biological and diagnostic applications. The chip was fabricated in a cyclic polyolefin by hot-embossing with a master mold. The solid phase consisted of a porous monolithic polymer column impregna...

A liquid chromatographic method with comfirmation by capillary electrophoresis was used to determine 12 sulfonylurea herbicides in agricultural water. Analysis of 3 different water matrixes fortified at 2 levels gave good recoveries with adequate sensitivity at the 0.1 ppb level. A portion of the water was acidified with acetic acid and loaded onto an RP-102 solid-phase extraction (SPE) cartrid...

Solid-Phase Extraction (SPE) is a sample preparation method that is practised on numerous application fields due to its many advantages compared to other traditional methods. SPE was invented as an alternative to liquid/liquid extraction and eliminated multiple disadvantages, such as usage of large amount of solvent, extended operation time/procedure steps, potential sources of error, and high ...

An UHPLC-MS/MS multiresidue method based on an on-line solid phase extraction (SPE) procedure was developed for the simultaneous determination of 9 perfluorinated carboxylates (from 4 to 12 carbon atoms) and 3 perfluorinated sulphonates (from 4 to 8 carbon atoms). This work proposes using an on-line solid phase extraction before chromatographic separation and analysis to replace traditional met...

a simple and sensitive method has been developed for the preconcentration and determination of trace level of co(ii) using uv-vis spectrophotometry. β-cyclodextrin polymer modified with 1-(2-pyridylazo)-2-naphthol (pan) is used for the preconcentration of co(ii) from samples at ph 8.5. the polymer is synthesized and characterized using elemental analysis, ft-ir and sem analysis. the factors aff...

Mercury (Hg) causes hazardous cumulative effects in humans; like central nervous system disorders,hypertension and chromosomal aberrations. Therefore, due to high toxicity and bioaccumulationfactor, mercury determination and speciation in human blood is very important. A sensitive,accurate, precise and inexpensive method was demonstrated for preconcentration and speciationof ultra-trace mercury...

We present the first use of digital microfluidic techniques to perform on-chip solid phase extraction (SPE). The material used for SPE was a porous polymer monolith with 12-carbon functionality (C12 PPM) which was photopolymerized on-chip and used to desalt a peptide sample prior to nano-electrospray ionization mass spectrometric analysis (nano-ESI-MS). We anticipate this technique may be usefu...

Simultaneous quantitative analysis of 10 indole compounds, including indole-3-acetic acid (IAA, one of the most important naturally occurring auxins) and some of its metabolites, by high performance liquid chromatography (HPLC) and liquid chromatography-mass spectrometry (LC-MS) after solid-phase extraction (SPE) was reported for the first time. The analysis was carried out using a reverse phas...