Despite a well-characterized lack of specificity, pathologists routinely employ S100 in the diagnosis of neural crest-derived tumors. Recent studies have shown that Sox10 is a reliable marker of neural crest differentiation that is consistently expressed in schwannian and melanocytic tumors. We sought to validate these results in a larger series of soft tissue neoplasms of both neural crest and...

Soft tissue is defined as the complex of non epithelial extraskeletal structures of the body exclusive of the supportive tissue of the various organs and the hematopoietic/lymphoid tissue. It is composed of fibrous tissue, adipose tissue, skeletal muscle, blood and lymph vessels and peripheral nervous system. Soft tissue tumours constitute a large and heterogenous group of neoplasms. These tumo...

Primary immunodeficiencies (PID) are genetically determined irreversible disorders of structure and/or functions the immune system's cellular and humoral components, accompanied by frequent infectious diseases contributing to development malignant neoplasms. Lymphomas most oncological disease in PID patients: non-Hodgkin's lymphomas occur 60 % neoplasms cases, Hodgkin lymphoma - 20 %, leukemias...

background and objective: different mechanisms may lead to the development of soft tissue tumor-like lesions in the oral cavity. many of these lesions can be identified as specific entities on the basis of their histopathological features and are divided into fibrous, vascular, and giant cell types. the purpose of this study was to establish the relative prevalence of the different histopatholo...

conclusions lower extremity movement extent was carefully evaluated and, in respect to muscle strength, the patient was able to walk independently three months after the surgery. the patient’s balance was studied and the results showed moderate levels of stability. case presentation this is a case report concerning a patient who had septic arthritis in the knee area and so underwent soft tissue...

recent studies show significant reduction of postural stability in transtibial amputees (ttas) especially when a perturbation is applied. however, no record has been seen on the consequences of such perturbation on the stump-socket interface pressure (ssip). our objective was to investigate whether such perturbation impose excessive pressures on the stump. we were also interested on the type of...

introduction: peripheral reactive lesions of soft tissue are common oral lesions that dentists face during routine examinations. diagnosis and development of a treatment plan is difficult if dentists are not aware of the prevalence and clinical symptoms of these lesions. the frequency of these lesions differs across various populations. the aim of this study was to determine the frequency and d...

Granular cell tumors are rare soft tissue neoplasms, among which only 2% are malignant, arising from nervous tissue. Here we present a case of a large esophageal granular cell tumor with benign histopathological features which metastasized to the liver, but showing on positron emission tomography-computerized tomography standardized uptake value suggestive of a benign lesion.

Any medical diagnosis should take a multimodal approach, especially those involving tumour-like conditions, as entities that mimic neoplasms have overlapping features and may present detrimental outcomes if they are underdiagnosed. These case reports present diagnostic pitfalls resulting from overdependence on a single diagnostic parameter for three musculoskeletal neoplasm mimics: brown tumour...