INTRODUCTION Paraquat poisoning is characterized by multi-organ failure and pulmonary fibrosis with respiratory failure, resulting in high mortality and morbidity. The objective of this study was to identify predictors of mortality in cases of paraquat poisoning. Furthermore, we sought to determine the association between these parameters. METHODS A total of 187 patients were referred for man...

PURPOSE Severity scores including the Simplified Acute Physiology Score (SAPS) II and the Sequential Organ Failure Assessment (SOFA) score are used in intensive care units (ICUs) to assess disease severity, predict mortality and in research. We aimed to assess the predictive performance of SAPS II and the initial SOFA score for in-hospital and 90-day mortality in a contemporary international co...

BACKGROUND Multiple organ dysfunction and multiple organ failure (MOF) is still a major complication and challenge in the treatment of severely injured patients. The incidence varies decisively in current studies, which complicates the comparability regarding risk factors, treatment recommendations and patients' outcome. Therefore, we analysed how the currently used scoring systems, the MODS, D...

Introduction: The gut plays a major role in critical illness. Gastrointestinal problems occur frequently and are associated with an adverse outcome in critically ill patients despite that, gastrointestinal (GI) function is not included in any of the widely used scoring systems assessing organ failures in critical illness. Monitoring of intra-abdominal pressure (IAP) is gaining more and more pop...

OBJECTIVES Researchers have attempted to design various scoring systems to determine the severity and predict the outcome of critically ill patients. The present study aimed to evaluate the accuracy of SOFA score in predicting 1-month outcome of these patients in emergency department. METHODS The present study is a prospective cross-sectional study of >18 year old non-trauma critically ill pa...

Background Sepsis is a global threat but insufficiently studied in Southeast Asia. The objective was to evaluate management, outcomes, adherence to sepsis bundles, and mortality prediction of maximum Sequential Organ Failure Assessment (SOFA) scores in patients with community-acquired sepsis in Southeast Asia. Methods We prospectively recruited hospitalized adults within 24 h of admission wit...

INTRODUCTION Early alterations in tissue oxygenation may worsen patient outcome following traumatic haemorrhagic shock. We hypothesized that muscle oxygenation measured using near-infrared spectroscopy (NIRS) on admission could be associated with subsequent change in the SOFA score after resuscitation. METHODS The study was conducted in two Level I trauma centres and included 54 consecutive t...