نتایج جستجو برای: sodium compounds

تعداد نتایج: 405677  

Journal: :Nippon kagaku zassi 1961

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Journal: :ACS Medicinal Chemistry Letters 2015

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Journal: :Chemistry Letters 1975

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Journal: :Arkivoc 2006

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Journal: :Journal of the American Chemical Society 1909

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Journal: :Chemistry – A European Journal 2020

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Journal: :Journal of Japan Institute of Light Metals 1957

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2015
Ki Duk Park Xiao-Fang Yang Erik T. Dustrude Yuying Wang Matthew S. Ripsch Fletcher A. White Rajesh Khanna Harold Kohn

The functionalized amino acid, lacosamide ((R)-2), and the α-aminoamide, safinamide ((S)-3), are neurological agents that have been extensively investigated and have displayed potent anticonvulsant activities in seizure models. Both compounds have been reported to modulate voltage-gated sodium channel activity. We have prepared a series of chimeric compounds, (R)-7-(R)-10, by merging key struct...

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Journal: :iranian journal of pharmaceutical research 0
shima h. m. ebrahim ketabforoosh department of medicinal chemistry, faculty of pharmacy and pharmaceutical sciences research center, tehran university of medical sciences, tehran 14176, iran. mohsen amini department of medicinal chemistry, faculty of pharmacy and drug design and development research center, tehran university of medical sciences, tehran 14176, iran. mohsen vosooghi department of medicinal chemistry, faculty of pharmacy and pharmaceutical sciences research center, tehran university of medical sciences, tehran 14176, iran. abbas shafiee department of medicinal chemistry, faculty of pharmacy and pharmaceutical sciences research center, tehran university of medical sciences, tehran 14176, iran. ebrahim azizi molecular research laboratory, department of pharmacology and toxicology, faculty of pharmacy, medical sciences, university of tehran, tehran, iran. farzad kobarfard department of medicinal chemistry, shahid beheshti school of pharmacy, tehran, iran.

caffeic acid phenethyl ester(cape) suppresses the growth of transformed cells such as human breast cancer cells, hepatocarcinoma , myeloid leukemia, colorectal cancer cells, fibrosarcoma, glioma and melanoma. a group of heterocyclic esters of caffeic acid was synthesized using mitsunobu reaction and the esters were subjected to further structural modification by electrooxidation of the catechol...

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Journal: :iranian chemical communication 0
amira a. ghoneim chemistry department, faculty of science, zagazig university, zagazig, eg‐44519, egypt mohamed g. assy chemistry department, faculty of science, zagazig university, zagazig, egyp enaiat k. mohamed chemistry department, faculty of science, zagazig university, zagazig, egypt islam ragab chemistry department, faculty of science, zagazig university, zagazig, egyp

acylisothiocyanate (1) was allowed to react with benzylidene malononitrile producing oxazine derivative (2). also, compound (1) was reacted with sodium azide followed by refluxing with sodium ethoxide affording thiazinotetrazole derivative (4). the reaction of acetylacetone with compound (1) gave pyridine derivative (5) by intramolecular cycloaddition while it was reacted with n-methyl aniline ...

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