We focus on the problem of computing an -Nash equilibrium of a bimatrix game, when is an absolute constant. We present a simple algorithm for computing a 3 4 -Nash equilibrium for any bimatrix game in strongly polynomial time and we next show how to extend this algorithm so as to obtain a (potentially stronger) parameterized approximation. Namely, we present an algorithm that computes a 2+λ 4 -...

Recent studies indicate an accelerated progression of nonalcoholic steatohepatitis (NASH) in postmenopausal women. Hypercholesterolemia, an important risk factor for NASH progression, is often observed after menopause. This study examined the effects of estrogen on NASH in ovariectomized (OVX) mice fed a high-fat and high-cholesterol (HFHC) diet. To investigate the effects of estrogen deficienc...

We explore the interaction between evolutionary stability and lexicographic preferences. To do so, we define a limit Nash equilibrium for a lexicographic game as the limit of Nash equilibria of nearby games with continuous preferences. Nash equilibria of lexicographic games are limit Nash equilibria, but not conversely. Modified evolutionarily stable strategies (Binmore and Samuelson, 1992. J. ...

Introducing physical outcomes in coalitional games we note that they and social choice problems are equivalent (implying that so are the theory of implementation and the Nash program). This clarifies some misunderstandings (in regard to invariance and randomness), sometimes found in the Nash program.  1998 Elsevier Science S.A.

Non-alcoholic steatohepatitis (NASH) is a liver disease with the potential to lead to cirrhosis and hepatocellular carcinoma. Interleukin-6 (IL-6) has been implicated in the pathogenesis of NASH, with the so-called IL-6 'trans-signaling' cascade being responsible for the pro-inflammatory actions of this cytokine. We aimed to block IL-6 'trans-signaling', using a transgenic mouse that overexpres...

Background: Nonalcoholic steatohepatitis (NASH), a progressive stage of nonalcoholic fatty liver disease (NAFLD), is characterized by steatosis with inflammation. Investigations have suggested that oxidative stress may play an important role in the progress of NAFLD to NASH. To provide further insights into beneficial effects of antioxidants in NASH prevention, we employed two manganese-supero...

We study an intensively studied resource allocation game introduced by Koutsoupias and Papadimitriou where n weighted jobs are allocated to m identical machines. It was conjectured by Gairing et al. that the fully mixed Nash equilibrium is the worst Nash equilibrium for this game w. r. t. the expected maximum load over all machines. The known algorithms for approximating the so-called “price of...