Context.— Renal malignancies can be divided into cortical- and medullary-based tumors, the latter of which classically infiltrate renal parenchyma by extending between nonneoplastic structures. Although high-grade cortical tumors rarely exhibit same growth pattern, infiltrative morphology should elicit a differential diagnosis to considered in each case. However, these diagnoses challenging dis...

Clinical Trials Corner: Raising the SABR to Renal Cell Carcinoma

An elderly man presented with iron deficiency anemia and intermittent rectal bleeding. His past medical history was significant for a renal cell carcinoma resected 9 years earlier. After a colonoscopy and upper endoscopy were unremarkable, he underwent a small bowel capsule endoscopy, which revealed an ulcerated mass in the jejunum (Figure 1 and Video 1). Surgical resection was performed, and t...

Renal transplantation increases the probability of malignant tumors by about 2-4-fold overall with a much higher rate for renal epithelial malignancy. Renal tumors in renal transplant recipients are commonly conventional clear cell or papillary renal cell carcinoma. Clear cell papillary renal cell carcinoma is a recently described unique renal epithelial neoplasm with scant eosinophilic or mode...

BACKGROUND Renal cell carcinoma is the most frequent malignant neoplasia of the kidney accounting for 90 % of all renal solid tumors. Metastases from renal cell carcinoma are rarely located in the small bowel and generally their clinical presentation includes bleeding and obstruction. Intussusception in adults is an extremely rare pathological condition and only 30 to 35 % of small bowel intuss...

Recently multiple cutaneous leiomyomas, uterine leiomyoimatosis and renal cancer have been described as a cancer syndrome with autosomal dominant pattern of inheritance.We report a 79-year-old man who presented with multiple hyperkertotic erythematous nodules on his right leg with histological diagnosis of pilar leiomyoma. In his past medical history several systemic co...

Miliary mottling on chest radiography is seen in miliary tuberculosis, certain fungal infections, sarcoidosis, coal miner’s pneumoconiosis, silicosis, hemosiderosis, fibrosing alveolitis, acute extrinsic allergic alveolitis, pulmonary eosinophilic syndrome, pulmonary alveolar proteinosis, and rarely in hematogenous metastases from the primary cancers of the thyroid, kidney, trophoblasts, and so...

A 47-year-old man had a retroperitoneal tumor measuring 18 cm in maximum diameter of the left kidney that was diagnosed with computed tomography (CT)-guided needle biopsy as small cell carcinoma. Microscopically, the tumor cells showed immunohistochemical reaction for neural cell adhesion molecule antibodies. This patient with advanced renal small cell carcinoma and multiple metastatic lesions ...