The changes in sleep architecture, heart rate and respiratory rate to hyoscine butylbromide (HBB), a peripherally acting anticholinergic was studied. These effects were compared with that of atropine sulphate, a drug known to cross the blood brain barrier. The study followed a single blind cross over design with a one week washout period. Atropine sulphate (0.4 mg) and HBB (10 mg) were given in...

It is becoming increasingly apparent that sleep plays an important role in the maintenance, disease prevention, repair, and restoration of both mind and body. The sleep and wake cycles are controlled by the pacemaker activity of the superchiasmic nucleus in the hypothalamus but can be disrupted by diseases of the nervous system causing disordered sleep. A lack of sleep has been associated with ...

sleep disorders in children can lead to considerable complications. in some mental disorders including autism, it has more importance. despite the importance of sleep in children developments and lives, few researches have conducted in this area therefore this research is going to investigate sleep behavioral disorders in children and compare with normal children. research design was causal-com...

background: sleep disturbance is a common complaint of patients undergoing methadone maintenance therapy (mmt). there are limited studies about the effect of different treatments on insomnia due to mmt. in this study, we evaluated the effect of cognitive-behavioral treatment for insomnia (cbti) on sleep disorders in patients undergoing mmt. methods : twenty-two patients with insomnia due to mmt...

Stereotactic surgery with lesioning or deep brain stimulation directed to the ventralis intermedius nucleus of the thalamus is a well-recognized treatment for medically intractable tremor. A patient developed the rare complication of severe insomnia, easy awakening, and lack of slow-wave sleep after thalamotomy/deep brain stimulation implantation. This complication underscores the role of thala...

BACKGROUND The relationship between substance use and sleep is bidirectional. Substance use directly causessleep disturbances, and sleep problems are a critical factor in substance-use relapse. METHODS This study evaluated sleep disorders in 65 methadone maintenance treatment (MMT) patients, and61 opium-dependent patients who did not receive any treatment between September 2011 and July 2012 ...

Hypersomnia, a complaint of excessive daytime sleep or sleepiness, affects 4% to 6% of the population, with an impact on the everyday life of the patient Methodological tools to explore sleep and wakefulness (interview, questionnaires, sleep diary, polysomnography, Multiple Sleep Latency Test, Maintenance of Wakefulness Test) and psychomotor tests (for example, psychomotor vigilance task and Ox...

background: as sleep has a critical role in health and social function and also, changes in women's sleep patterns can be the first indicator of mood disorders this study was conducted to investigate the sleep disorders among women with premenstrual dysphoric disorder. methods: in this study, using standard tools of general sleep questionnaire (gsq) and berlin questionnaire, sleep disorders amo...

normal 0 false false false en-us x-none ar-sa background: circadian rhythm sleep disorders are a presentation of sleep disorders in patients with multiple sclerosis (ms). this study aims to compare this problem in ms patients with healthy people and to determine its association with chronic fatigue in ms patients. materials and methods: a case-control study was performed on 120 ms patients and ...