objective(s): leishmaniasis is a complex parasitic disease that represents a major public health problem. despite numerous attempts over the past decades, yet there is no effective vaccine against human leishmaniasis probably due to the lack of suitable adjuvants. in this study, a first generation liposomal-based leishmania vaccine was developed using soluble leishmania major antigens (sla) and...

The sand-blasting and acid etching (SLA) method can fabricate a rough topography for mechanical fixation and long-term stability of titanium implant, but can not achieve early bone healing. This study used two kinds of plasma treatments (Direct-Current and Radio-Frequency plasma) to modify the SLA-treated surface. The modification of plasma treatments creates respective power range and differen...

The process of photopolymer stereo-lithography (SLA) provides a unique opportunity for the rapid prototyping of investment castings having both high surface quality and complex geometry from both ferrous and non-ferrous metals. A specific internal honeycomb structure gives a combination of high pattern stiffness needed for precise replication of geometry by investment shell molds with an extrem...

MHC class I molecules and beta(2)-microglobulin (beta(2)m) are membrane glycoproteins that present peptide Ags to TCRs, and bind to inhibitory and activating receptors on NK cells and other leukocytes. They are involved in the discrimination of self from non-self. Modification of these molecules in the placenta benefits pregnancy, but little is known about their genes in the uterus. We examined...

The continued trend of globalization and technology improvement like the internet and transportation have spawned an increasing number of complex service chains that span across local, regional and national boundaries. Service level agreement (SLA) plays a crucial role in gluing service chains together. In that regard, this paper provides a complete guidance of end-to-end lifecycle management o...

Objective(s): Leishmaniasis is a complex parasitic disease that represents a major public health problem. Despite numerous attempts over the past decades, yet there is no effective vaccine against human leishmaniasis probably due to the lack of suitable adjuvants. In this study, a first generation liposomal-based Leishmania vaccine was developed using soluble Leishmania major antigens (SLA) and...

Quality-of-service and SLA guarantees are among the major challenges of cloud-based services. In this paper we first present a new cloud model called SLAaaS – SLA aware Service. SLAaaS considers QoS levels and SLA as first class citizens of cloud-based services. This model is orthogonal to other SaaS, PaaS, and IaaS cloud models, and may apply to any of them. More specifically we make three con...

THE SLA (swine leukocyte antigen, MHC: SLA) genes are the most important determinants of immune, infectious disease and vaccine response in pigs; several genetic associations with immunity and swine production traits have been reported. However, most of the current knowledge on SLA is limited to gene coding regions. MicroRNAs (miRNAs) are small molecules that post-transcriptionally regulate the...

OBJECTIVE(S) Soluble Leishmania antigens (SLA) provide suitable protection against leishmaniasis in murine model when delivered by an appropriate delivery system. Liposomes have been shown to be suitable vaccine delivery systems against leishmaniasis, however, the phospholipase-A (PLA) activity of SLA is a drawback to prepare a stable liposomal SLA. One strategy to overcome this problem might b...

The cloud computing as a ubiquitous paradigm could provide different services for internet users and Information Technology (IT) companies through datacenters located around the world. However, cloud provider faces several problems such as security and privacy issues in cloud datacenters. Hence, cloud provider has to handle security challenges to gain more profit. In this paper, a SecurityAware...