Background: Many factors are currently being identified as potential inductors of skin cancer in patients after a liver transplant, among them, immunosuppressive regimen. Objective: To study the factors that influence the incidence of skin cancer in patients after liver transplant. Methods: We have carried out a retrospective and observational study with 170 transplanted patients who had un...

Organ/tissue transplantation has become an effective therapy for end-stage diseases. However, immunosuppression after transplantation may cause severe side effects. Donor-specific transplant tolerance was proposed to solve this problem. In this study, we report a novel method for inducing and maintaining heart allograft tolerance rats. First, we induced indefinite vascularized hind-limb allogra...

introduction : recipients of renal transplants are susceptible to kaposi's sarcoma (ks) as a result of treatment with immunosuppressive drugs. ks is one of the most common post transplant malignancies. variety of factors appear to contribute to the development of ks including: genetic factors, sex hormones, immunosuppression and oncogenic viruses.this study present three cases of renal transpla...

The skin pathology seen in graft recipients is unique because they are usually seen in patients who have a long history of renal disease, where the characteristic lesions seen in pre-terminal failure followed by dialysis-induced skin pathology had developed. The skin changes after renal transplantation partially replace, and partially are superimposed upon, the skin lesions characteristic for t...

Background: The application of mesenchymal stem cells in the healing of chronic wounds is one of the most challenging issues in cell therapy. The present study investigated the efficacy of intradermal injection of umbilical cord Wharton's Jelly-derived mesenchymal stem cells in diabetic wound healing using ultrasound imaging in an animal model. Methods: During this experimental laboratory stud...

Sir, We read the article by Belloni-Fortina et al. (1) with great interest. This retrospective study focused on the incidence of, and risk factors for, skin complications among liver transplant patients. They concluded that in these recipients the risk of premalignant and malignant skin lesions was lower than that of other solid organ transplants. Although organ transplant recipients are predis...

Skin transplanted as a homograft from one animal to a genetically dissimilar animal of the same species is rejected after nine to twelve days, probably because of actively acquired immune reactions (Medawar 1944, 1945; Billingham, Brent and Medawar 1954; Billingham, Brent, Medawar and Sparrow 1954). The acquired resistance is termed either transplantation immunity (Billingham, Brent and Medawar...

There are no published clinical studies evaluating the impact of warts on quality of life after transplantation. The aim of this study was to determine the frequency of self-reported skin warts and skin cancer and their impact on quality of life in kidney transplanted patients, as measured with the Dermatology Life Quality Index (DLQI). Of 740 patients with a functioning renal allograft and wer...

Background and objective: Renal transplantation is an appropriate treatment for end stage renal disease and helps prolongation of patients survival with better quality, but immunosuppressive drugs that are used for inhibition of rejection after transplantation may cause some adverse effects in other organs such as the skin. Apparently, early recognition of those side effects and their app...