Brucellosis is a zoonotic infectious disease of worldwide distribution and is still endemic in some developing countries. Brucellosis is a systemic disease in which any organ or system of the body can be involved. The most commonly affected systems are the locomotor, gastrointestinal, genitourinary, haematological, cardiovascular, respiratory, and central nervous systems. Cutaneous manifestatio...

iabetes Mellitus (DM) refers to a group of metabolic disorders with a common presentation of hyperglycemia. There are two common types of DM. In Type 1, there is absolute or neartotal insulin deficiency; while in type 2, the problem originates from insulin resistance, impaired insulin secretion and raised glucose production (1). Skin disorders are common in diabetic patients and the prevalence ...

Both acute and chronic liver disease can manifest on the skin. The appearances can range from the very subtle, such as early finger clubbing, to the more obvious such as jaundice. Identifying these changes early on can lead to prompt diagnosis and management of the underlying condition. In this pictorial review we will describe the skin manifestations of specific liver conditions illustrated wi...

OBJECTIVES To investigate skin manifestations of the polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, and skin changes (POEMS) syndrome and their correlation with serum vascular endothelial growth factor (s-VEGF-A) levels and to describe the impact of autologous peripheral blood stem cell transplantation (aPBSCT) on these manifestations and the correlation with s-VEGF-A leve...

The pediatrician is faced with evaluating a panoply of skin rashes, a subset of which may be induced by food allergy. Acute urticaria is a common manifestation of an allergic skin response to food, but food is rarely a cause of chronic urticaria. Approximately one third of infants/children with moderate to severe atopic dermatitis have food allergy. Although diagnosis of acute urticaria provoke...

Background: Diabetes mellitus affects all systems of the body. Skin is also frequently involved. The aim of the study was to assess the frequency of various skin manifestations in patients with diabetes mellitus. Methods: This descriptive study was conducted at the out-patient diabetic clinics at Aga Khan University Hospital, Karachi. One hundred consecutive patients, both male and female suffe...

The recognition of the bacteria family Bartonellaceae , genus Bartonella has expanded during the past decade from the single Bartonella bacilliformis to 17 currently identified species (Table 1). At least six of these ( B. bacilliformis, B. henselae, B. quintana, B. elizabethae , B. clarridgeiae and B. vinsonni arupensis ) are responsible for human diseases. 1,2 The growing knowledge in this fi...

The conception of the reticulo-endothelial system belongs to the realm of experimental pathology. The reticuloses, a group of disorders primarily affecting that system are, therefore, a concept of pathology and their clinical manifestations must be diverse. Indeed, even among pathologists, opinions are divided as to the criteria which govern admission to the group. It would be widely conceded t...

Endocrine diseases may result in changes in cutaneous function and morphology, which cause various skin manifestations, including nonspecific or pathognomonic signs. Some of these manifestations are already known dermatologic diseases with only increased frequency in this patient group. As a result the skin may the play role of a screen displaying endocrine disorders, either due to hormone exce...