نتایج جستجو برای: sinonasal undifferentiated carcinoma

تعداد نتایج: 405675  

Journal: :Head & neck 2014
Andreas Schröck Friederike Göke Patrick Wagner Maike Bode Alina Franzen Sebastian Huss Abbas Agaimy Stephan Ihrler Robert Kirsten Glen Kristiansen Friedrich Bootz Claudia Lengerke Sven Perner

BACKGROUND Despite multimodal treatment, sinonasal malignancies have an unfavorable prognosis. The purpose of this study was to elucidate if these tumors harbor amplifications of the fibroblast growth factor receptor 1 (FGFR1) gene, which has recently been identified as a potential therapeutic target in squamous cell lung cancer. METHODS One hundred twelve primary tumors (including squamous c...

Journal: :Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques 2010

Journal: :The Laryngoscope 2010
Ashley G O'Reilly David J Schembri Wismayer Eric J Moore

Originally described in 1986, sinonasal undifferentiated carcinoma (SNUC) is a rare and aggressive malignancy of the nasal cavity and paranasal sinuses. Although the majority of patients diagnosed with SNUC have a poor outcome, there are patients that, with treatment, do not develop recurrences and are essentially cured of their disease. Currently, there are no prognostic factors in the literat...

Journal: :Journal of Neurological Surgery Part B: Skull Base 2017

Journal: :Oral oncology 2016
Tom P van der Laan René Iepsma Max J H Witjes Bernard F A M van der Laan Boudewijn E C Plaat Gyorgy B Halmos

The aim of this meta-analysis was to provide treatment guidelines for sinonasal neuroendocrine carcinoma (SNC) by combining all available data in the literature. A literature search for all studies concerning SNC was performed against the MEDLINE and EMBASE databases. Available clinical data was normalized, pooled, and statistically analyzed. A total of 701 cases of SNC were available for analy...

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