modeling of fermentation processes is so complicated and uncertain; therefore it is necessary to provide a robust and appropriate dynamic optimization method. in order to obtain the maximum amount of yeast (saccharomyces cerevisiae), the bioreactor must be operated under optimal conditions. to determine substrate feeding in a fed-batch bioreactor, a simulated annealing (sa) approach was examine...

Cloud computing is a new computing paradigm which uses the combination of two concepts i.e. “software-asa-service” and “utility computing”, provides convenient and on-demand services to requested end users by instantiating the infrastructure and using the resources dynamically. Load balancing in Cloud computing is still one of the main challenges for the researchers. As load balancing distribut...

We investigate a new method (QTA-PIMC) for global optimization on complex potential energy surfaces which combines the path integral Monte Carlo method with quantum and thermal annealing. This method is applied to the BLN protein model (Honeycutt, J. D.; Thirumalai, D. Biopolymers 1992, 32, 695). We show that this new approach outperforms simulated (thermal) annealing (SA) and that in fact SA i...

The aim of this study is to improve searching capability of simulated annealing (SA) heuristic through integration of two new neighborhood mechanisms. Due to its ease of formulation, difficulty to solve and various real life applications several Travelling Salesman Problems (TSP) were selected from the literature for the testing of the proposed methods. The proposed methods were also compared t...

Simulated Annealing and Genetic Algorithm are two well-known metaheuristic algorithms for combinatorial optimization. These two methods have also been used for solving constrained continuous problems. In this study, five constrained continuous problems have been solved both Simulated Annealing (SA) and Genetic Algorithm (GA). Optimum results have been compared with real optimum values obtained ...

The permutation flow shop scheduling problem (PFSP) is one of the most well known and well studied production scheduling problems with strong industrial background. Most scheduling problems are combinatorial optimization problems which are too difficult to be solved optimally, and hence heuristics are used to obtain good solutions in a reasonable time. The specific goal of this paper is to inve...

Optimization problems for biomechanical systems have become extremely complex. Simulated annealing (SA) algorithms have performed well in a variety of test problems and biomechanical applications; however, despite advances in computer speed, convergence to optimal solutions for systems of even moderate complexity has remained prohibitive. The objective of this study was to develop a portable pa...

In this paper we present a hybrid strategy developed using genetic algorithms (GAs), simulated annealing (SA), and quantum simulated annealing techniques (QSA) for the discrete time–cost trade-off problem (DTCTP). In the hybrid algorithm (HA), SA is used to improve hill-climbing ability of GA. In addition to SA, the hybrid strategy includes QSA to achieve enhanced local search capability. The H...

The Graph k-Colorability Problem (GCP) is a well known NP-hard problem which consist in finding the k minimum number of colors to paint the vertices of a graph in such a way that any two vertices joined by an edge have always different colors. Many years ago, Simulated Annealing (SA) was used for graph coloring task obtaining good results; however SA is not a complete algorithm and it not alway...