The statistical methodology for the design and analysis of clinical Phase II dose-response studies, with related software implementation, is well developed for the case of a normally distributed, homoscedastic response considered for a single timepoint in parallel group study designs. In practice, however, binary, count, or time-to-event endpoints are encountered, typically measured repeatedly ...

introduction: the framework convention tobacco control (fctc) is designed by world health organization (who), in response to the globalization of the tobacco epidemic, in 2003. all treaty signatories including iran adopted to perform it during 3 years. this study was performed to design a model for evaluation of the implementation of this treaty in iran. methods: this study was a qualitative st...

The motivation for this work is to propose a first thorough review of dough rheological models used in numerical applications. Although many models have been developed to describe dough rheological characteristics, few of them are employed by researchers in numerical applications. This article reviews them in detail and attempts to provide new insight into the use of dough rheological models.

background: in modern life, the incidence of traumatic injuries increases daily. in accidents which lead to trauma, massive bleeding is the main cause of death. nowadays, many different chemical and herbal agents are available for quick control of bleeding. objectives: in this study, we compare the effectiveness of two different types of chemical agents for control of bleeding in an animal mode...

We developed a new semi-supervised EM-like algorithm that is given the set of objects present in eachtraining image, but does not know which regions correspond to which objects. We have tested thealgorithm on a dataset of 860 hand-labeled color images using only color and texture features, and theresults show that our EM variant is able to break the symmetry in the initial solution. We compared...

the main objective of this article is to present a comparative study of capital assets pricing models (capm) with extrapolating capital assets pricing models (x-capm) of companies admitted in tehran exchange market which is accomplished for the first time by investigators of this research in iran. accordingly, the statistical population under study of this research includes all companies admitt...

this paper is a translation of a chapter of the hook written by jonathan e. ingersoll jr. the farsi translation will he of great help to iranian students studying option pricing models.

the present research was planned to evaluate the skill of linear stochastic models known as arima and multiplicative seasonal autoregressive integrated moving average (sarima) model in the quantitative forecasting of the standard runoff index (sri) in karkheh basin. to this end, sri was computed in monthly and seasonal time scales in 10 hydrometric stations in 1974-75 to 2012-13 period of time ...

b a c k g r o u n d & aim: the excess hazard rate proposed by andersen and vaeth may underestimate the long-term excess hazard rate for cancer survival. zahl explained the phenomenon by continuous selection of the most robust individuals after diagnosis. he applied correlated inverse gaussian and gamma  frailty  models  to estimate  excess  intensity  and reached  a better  estimate  of the rat...

although the majority of the patients with traumatic brain injury presents with injuries involving the extremities, there was a clear paucity of adequate experimental polytrauma models. to close this gap, we conducted several studies to establish two different polytrauma mice models including both closed and open traumatic brain injury. male c57bl mices with a mean weight of 23g were anesthetiz...