OBJECTIVES The aim of this study is to evaluate the prevalence and diversity of extended-spectrum beta-lactamases (ESBLs) in Enterobacter cloacae clinical isolates collected from Algerian hospitals and to verify the association with qnr genes. METHODS MICs were determined by Etest for isolates giving positive double-disc synergy tests, and all isolates were screened by PCR and sequenced, resp...

La Ciudad de México (CDMX) enfrenta una situación vulnerabilidad sociohidrológica (SHV) debido a la creciente escasez agua. Este estudio evalúa SHV Alcaldía Cuajimalpa con base en construcción social del espacio. El estrés hídrico y capacidad adaptativa son elementos clave para comprender las condiciones materiales, ambientales sociales un territorio. Se propone metodología mixta como eje acció...

The goal of this study was to provide a measurement of the true internal diameter (ID) of various surgical heart valves (SHV) to facilitate the valve-in-valve (VIV) procedure. During a VIV procedure, it is important to choose the right of the transcatheter heart valve (THV). Most users use the stent ID of an SHV to select the appropriate THV size. Echocardiography and computed tomography measur...

The TEM-1 and SHV-1 beta-lactamases are important contributors to resistance to beta-lactam antibiotics in gram-negative bacteria. These enzymes share 68% amino acid sequence identity and their atomic structures are nearly superimposable. Extended-spectrum cephalosporins were introduced to avoid the action of these beta-lactamases. The widespread use of antibiotics has led to the evolution of v...

Klebsiella pneumoniae K6 (ATCC 700603), a clinical isolate, is resistant to ceftazidime and other oxyimino-beta-lactams. A consistent reduction in the MICs of oxyimino-beta-lactams by at least 3 twofold dilutions in the presence of clavulanic acid confirmed the utility of K. pneumoniae K6 as a quality control strain for extended-spectrum beta-lactamase (ESBL) detection. Isoelectric-focusing ana...

OBJECTIVES Klebsiella pneumoniae is a gram-negative rod bacterium, a known cause of community-acquired bacterial pneumonia and is an important hospital-acquired pathogen that causes severe morbidity and mortality. The aim of this study was to identify the TEM and SHV genes in K. pneumoniae isolated from cockroaches obtained from hospitals. METHODS In this study, 250 cockroaches were collected...

Background & objectives: Extended spectrum β-lactamases (ESBLs) are often plasmid mediated derived from mutations in the classic TEM and SHV genes by one or more amino acid substitution around the active site. Detection of TEM and SHV genes by molecular methods in ESBL producing bacteria and their pattern of antimicrobial resistance can provide useful information about its epidemiology and risk...