Background: Dengue fever is a benign syndrome caused by arthropod borne viruses which transmitted infective bite of particular mosquito known as Aedes aegypti, day time biting mosquito, the principal vector disease. Although liver not major target organ, hepatic dysfunction well recognised and can be used an early predictor to assess dengue severity looking at ratio serum glutamic-oxaloacetic t...

Health practitioners all over the world have studied liver injury caused by drug side effects. Excessive production of free radicals causes cell damage, which has implications for pathological conditions in both humans and animals. Omega-3 fatty acids are a component fish that can work as hepatoprotective agents. Eel (Anguilla bicolor) is known to contain omega-3 including eicosapentaenoic acid...

This research aimed to give an overview about the examination results of Serum Glutamic Oxaloacetic Transaminase (SGOT) and Pyruvic (SGPT) levels farmers at Padengo Village, sub-district Dengilo district Pohuwato.
 used a quantitative approach with descriptive analysis. The type data was primary in form secondary were from literature, books documents. sampling simple random technique total...

Dengue Haemorrhagic Fever (DHF) merupakan penyakit demam yang disebabkan oleh gigitan nyamuk Aedes aegypti dan albopictus. Terhitung sejak tahun 1968-2009, World Health Organization (WHO) mencatat negara Indonesia sebagai dengan kasus DHF tertinggi di Asia Tenggara menempati urutan kedua. Pasien penderita sering juga ditemukan adanya keterlibatan organ salah satunya adalah hepar. Virus penyebab...

Serum alpha-fetoprotein levels were measured serially by radioimmunoassay in 32 patients with acute viral hepatitis. With one exception, the levels were increased during the course of the illness. Raised concentrations of the protein occurred almost equally in patients with and without the hepatitis-B antigen. In the majority of patients the rise was modest but in seven levels were reached at w...

Aim: This study was aimed to evaluate the duration dependent study to develop Plasmodium berghei infection in in vivo system. Methods: 200μl of infected blood containing 1X10 5 parasites was challenged in Swiss mice intraperitoneally for 5, 10 and 15 days. After sacrifice, parasitemia, O2 .generation, NADPH oxidase activity, NO generation of lymphocyte; MDA level, TrxR activity and haemolytic a...

A single dose of CCl4 (1 ml/kg body weight, po in corn oil) increased the levels of SGOT (serum glutamate oxaloacetate transaminase), SGPT (serum glutamate pyruvate transaminase), LDH (lactate dehydrogenase), glutathione-S-transferase and depletion in reduced glutathione, glutathione peroxidase and glutathione reductase. It also caused enhancement in the levels of lipid peroxidation (LPO) and D...

Thirty one children with typhoid fever aged 2 months to 12 years and blood culture positive for multidrug resistant S. typhi were prospectively studied for their hepatic functions at the time of hospitalization and 2-3 weeks after completion of antibiotic therapy. Hepatic manifestations included hepatomegaly (51.6%); jaundice (16.1%); raised levels of serum glutamic oxaloacetic transaminase (SG...

Diabetes is a group of metabolic disease and associated with impaired glucose metabolism, resulting from defect in insulin secretion, action and both. The present study was undertaken to evaluate the insulin secretion and anti-oxidative potential of Ocimum sanctum extract in diabetic rats. The results showed that extensive oxidative stress is generated in tissues of diabetic rats, increased the...

The objective of present study was to explore the hepatoprotective and antioxidant profile of Citrullus colocynthis fruits. Hepatoprotective profile of methanolic extract of Citrullus colocynthis fruits (MECCF) was investigated on rats, which were made hepatotoxic using paracetamol. The antioxidant profile of MECCF was evaluated by conducting Catalase, Super oxide Dismutase, Lipid Peroxidation ...