نتایج جستجو برای: sgca
تعداد نتایج: 49 فیلتر نتایج به سال:
In order to succeed in the fulfillment of clients ever increasing expectations, embedded systems companies are entering the area of multitasking environments. As memory is still a primary concern to achieve a good tradeoff between system performance and cost, we cannot rule out dynamic linking techniques since they reduce memory consumption at runtime. Using parameters from an ADL model of the ...
BACKGROUND Autosomal recessive limb-girdle muscular dystrophies (LGMD2) include a number of disorders with heterogeneous etiology that cause predominantly weakness and wasting of the shoulder and pelvic girdle muscles. In this study, we determined the frequency of LGMD subtypes within a cohort of Czech LGMD2 patients using mutational analysis of the CAPN3, FKRP, SGCA, and ANO5 genes. METHODS ...
The primary purpose of this research is to examine the hypothesis that reactive oxygen species generated by estrogen quinonoids are the main source for the formation of aldehydic DNA lesions (ADL) in genomic DNA. ADL induced by quinonoid metabolites of 17beta-estradiol (E2), e.g. 4-hydroxyestradiol (4-OH-E2), 2-hydroxyestradiol (2-OH-E2), estrogen-3,4-quinones (E2-3,4-Q) and estrogen- 2,3-quino...
Context: Over the last two decades, software architecture has introduced a new trend in software development. This new trend has completely changed the normal methods and practices of software engineering. The focus has become the architectural elements rather than code and sub-routines. Architecture description languages (ADLs) have been proposed for this kind of architecture based software de...
Background Accurate estimation of prognosis in multimorbid hospital patients could improve quality of care. This study aims to determine the relative importance and added value of a performance-based activities of daily living (ADL) measure with regard to mortality prediction. Methods 200 inpatients, aged over 60 years, were recruited at the Department of General Internal Medicine at a tertiary...
Postoperative ileus (POI) in patients undergoing abdominal surgery is associated with signifi cant morbidity. In 2008, alvimopan (Entereg®) was approved by the Food and Drug Administration (FDA), and is the only available POI therapy in the United States for patients undergoing bowel resection. Data from preclinical studies demonstrate that alvimopan and its primary metabolite, ADL 08-0011, beh...
Abstract Study question Does cryopreservation impact on transcriptome of conventional frozen human spermatozoa? Summary answer The sperm alters pathways important for fertility, although the upregulation some genes can compensate harmful effects freezing. What is known already Sperm a widely used procedure storing gametes later use, preserving fertility in patients before gonadotoxic treatments...
On the basis of their differential location within dermis and discrete changes in gene protein expression, two major fibroblast subtypes (papillary reticular) have traditionally been distinguished. In last 3 years, a number research groups begun to address transcriptomic heterogeneity human skin cells at single-cell level by determining mRNA levels expressed genes through RNA sequencing technol...
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