Microarray gene expression data play a vital in biological processes, gene regulation and disease mechanism. Biclustering in gene expression data is a subset of the genes indicating consistent patterns under the subset of the conditions. Finding a biclustering is an optimization problem. In recent years, swarm intelligence techniques are popular due to the fact that many real-world problems are...

Ma and McClintock reiterate our observation that the TRS data during this time do not follow a linear trend — with an obvious upturn in 2006 through 2007 and a smaller downturn in 2002 through 2003 — and question our use of a linear model to describe these data. In our analyses, we examined a segmented regression approach (3) to address this nonlinearity, using a theoretical break point at 2006...

BACKGROUND Within the last decade, confocal microscopy has become a valuable non-invasive diagnostic tool in imaging human skin in vivo. Of the two different methods that exist, reflectance confocal microscopy (RCM) displays the backscattering signal of naturally occurring skin components, whereas fluorescence confocal microscopy (FCM) provides contrast by using an exogenously applied fluoresce...

As students’ academic language ability grows, they are expected to move from summarizing or retelling works of literature to studying texts critically. With this comes the demand for more developed literacy skills or, as those working from a systemic functional linguistic perspective would argue, an increase in the students’ resources for making meaning in an ever-widening variety of contexts (...

The identification and validation of gene-gene interactions is a major challenge in human studies. Here, we explore an approach for studying epistasis in humans using a Drosophila melanogaster model of neonatal diabetes mellitus. Expression of the mutant preproinsulin (hINS(C96Y)) in the eye imaginal disc mimics the human disease: it activates conserved stress-response pathways and leads to cel...

AIMS Portugal has one of the lowest rates of primary percutaneous coronary intervention (p-PCI) in Western Europe. This study assessed the progress of Portuguese p-PCI performance indicators one year after Portugal joined the Stent for Life (SFL) initiative. METHODS AND RESULTS Two national surveys were carried out, each covering a period of one month: the first when Portugal joined the SFL i...

Recently, the sparse representation based classification methods have received particular attention in the classification of hyperspectral imagery. However, current sparse representation based classification models have not considered all the test pixels simultaneously. In this paper, we propose a hyperspectral classification method with spatial filtering and `2,1 norm (SFL) that can deal with ...

This research paper applies systemic functional linguistics (SFL) to analyze the transitivity patterns of Changez’s character in Mohsin Hamid’s novel, The Reluctant Fundamentalist. study aims examine how evolve and shift over course narrative, particularly relation his changing ideological stance identity. Using Halliday’s SFL framework, analysis reveals that reflect evolving agency, worldview,...

A network governing DNA integrity was identified in yeast by a global genetic analysis of synthetic fitness or lethality defect (SFL) interactions. Within this network, 16 functional modules or minipathways were defined based on patterns of global SFL interactions. Modules or genes involved in DNA replication, DNA-replication checkpoint (DRC) signaling, and oxidative stress response were identi...