CONTEXT Thyroid hormones have a dramatic effect on human behavior. However, their role on sexual behavior and performance has seldom been investigated in men. OBJECTIVE The objective of this study was to evaluate the prevalence of sexual dysfunctions in patients with hyper- and hypothyroidism and their resolution after normalization of thyroid hormone levels. DESIGN AND SETTING We conducted...

Hormones are crucial systemic players and act at different sites of the entire body including the brain. The brain is not only the target of hormone action, but also serves as the “conductor” of the “neuro-endocrine symphony”. Changes in neuronal activity, such as seizures in epileptic patients, may affect hormonal regulation and secretion. In turn, hormones modify susceptibility to develop sei...

Choosing a mate requires a way to turn sexual arousal into sexual action. A recent paper identifies a hormone receptor that acts as a molecular gatekeeper in reproductive decisions. Focusing on mate-choice mechanisms may clarify longstanding evolutionary puzzles in sexual selection and speciation.

which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. For the first time in Asia, in July 2011, Korea introduced using chemical castration on sexual offenders. Under the current law, perpetrators of sexual crimes against minors aged less than 16 yr are subject to chemical castration. There have been growing cal...

Drawing on physiological research, this study explores disclosures after sexual activity, or ‘‘pillow talk.’’ Oxytocin, better known as the ‘‘bonding hormone,’’ has been associated with physical affection and intimacy. While the hormone was originally studied for its role in childbirth, recent work has started to explore oxytocin’s other effects, such as decreasing stress, decreasing perception...

To clarify whether sexual arousal could be enhanced by hypoxia, and to explain the pathogenesis of autoerotic death (AED)/autoerotic asphyxiation (AEA), we investigated the molecular-biological and hormonal interactions in male rats between hypoxia (10% O2) and sexual stimulation (placing male rats with oestrous female rats) using hypothalamus tissue and serum. Serum oxytocin concentration was ...

Background Hypopituitarism as a result of PROP1 (prophet of PIT1) mutation represents the most common genetic cause of combined deficiency of pituitary hormones and due to growth retardation it is typically diagnosed in childhood. Case description We present a unique case report of a prepubertal woman with growth retardation in whom combined pituitary hormone deficiency [central hypopituitari...

Galanin-like peptide (GALP) is a recently described neuropeptide, which shares a partial sequence identity with galanin but is derived from a separate gene. Central injections of GALP stimulate the secretion of gonadotropin-releasing hormone (GnRH) and luteinizing hormone (LH) and induce the expression of Fos in several brain areas known to regulate male sexual behavior in the rat. We postulate...