Background and Objective: P53 is a suppressive gene that plays a key role in DNA repair and apoptosis. The purpose of this study was to investigate the effect of P53 protein over-expression and some clinicopathological factors on the esophageal squamous cell carcinoma (SCC) response to neoadjuvant chemoradiotherapy. Patients and Methods: In this retrospective cohort study, 44 patients with loc...

background: adipose derived stem cells (ascs) provoke the accumulation and expansion of regulatory t cells, leading to the modulation of immune responses in tumor microenvironment. objective: to assess the effect of tumoral ascs on the trend of regulatory t cells differentiation. methods: peripheral blood naïve cd4+ t cells were co-cultured with ascs derived from breast cancer or normal breast ...

abstract  background: resection of the distal end of the radius is indicated in the treatment  of locally aggressive primary benign and malignant bone tumors. the aim of this study  was to evaluate the technique of osteoarticular allograft reconstruction of the distal radius after wide excision of a giant-cell tumor.  methods: we analyzed 15 patients retrospectively who had reconstruction of th...

Granulosa cell tumor, a sex cord stromal estrogen secreting tumor presents with vaginal bleeding and is seen in all ages. It accounts for <5% of ovarian neoplasm. We reported rare case granulosa postmenopausal woman undergoing staging laparotomy total abdominal hysterectomy bilateral salpingo-oopherectomy malignant which was complicated by torsion, rupture hemorrhagic ascitis. Any should aro...

background and objective: p53 is a suppressive gene that plays a key role in dna repair and apoptosis. the purpose of this study was to investigate the effect of p53 protein over-expression and some clinicopathological factors on the esophageal squamous cell carcinoma (scc) response to neoadjuvant chemoradiotherapy. patients and methods: in this retrospective cohort study, 44 patients with loca...

congenital epulis is a very rare benign soft-tissue tumor of uncertain histogenesis, which is also known as “gingival granular cell tumor of the newborn”. it occurs almost exclusively as a single tumor along the alveolar ridge of the maxilla in newborn females. although congenital epulis is strikingly similar to the more common adult granular cell tumor histologically, in contrast to the latter...

granular cell tumor (gct) was first described by abrikossoff in 1926. gct is a rarely seen soft tissue tumor and is generally benign. while the tumor can be seen in all parts of the body it is generally located on the head and neck region, and especially on the tongue. gct is rarely seen in the anal-perianal region. in accordance with literature this case was reported because it was thought to ...

intra-abdominal desmoplastic small round cell tumor is a rare entity with a few reports worldwide. this tumor commonly occurs in children and adolescent and occurrence in adult age group is very rare. here, we describe an adult male with symptoms of intestinal obstruction due to abdominal mass, located in splenic flexure. after resection, the diagnosis of intra-abdominal desmoplastic small roun...

normal 0 false false false en-us x-none ar-sa microsoftinternetexplorer4 there are a few case series of giant cell tumor (gct) in the spine and sacrum. gct in the thoracic vertebrae is even more exceptional in the medical literature. in this article we report a gct in a 25-year-old male who presented with progressive back pain and dyspnea. on contrast-enhanced multidetector computer tomography,...