Background: Serum insulin variations are occasionally observed in patients suffering infertility or gonad failure. The main purpose of the present study was to clarify the effects of gonadectomy and sex steroid hormone replacement on serum insulin level in rats. Materials and Methods: Male rats were divided into control, orchidectomized, and testosterone receiving orchidectomized animals. Femal...

Objective: To see how dose of Silymarin aqueous extracts affected prolactin hormone gene expression in pituitary glands and Androgen serum samples female experimental rats throughout nursing. Methods: 24 adult healthy, Two sets pregnant were created (12 each group) treated as follows for ten days postnatal. G 1 intubated orally distal water serving control while, 2 (200 mg\kg\day). Results: The...

OBJECTIVE This study was designed to detect the relation between serum progesterone and viability of pregnancy during the first trimester. MATERIAL AND METHODS Two hundred and sixty women during the first trimester of their pregnancies were hospitalised due to vaginal bleeding and/or abdominal pain and were included in this study. Criteria for inclusion in this study were: certain dates, foet...

The aim of this study was to identify a subgroup of pregnant women with asymptomatic hypercholanaemia of pregnancy (AHP), in which the relationship between alterations in the level and pattern of serum bile acids (BAs) and of progesterone plus progesterone metabolites could be investigated in the absence of overt impairment of hepatobiliary function. Cholanaemia and serum concentrations of prog...

BACKGROUND Our recent paper, based on a pilot cohort of 119 women, showed that serum progesterone <35 nmol/L was prognostic of spontaneous miscarriage by 16 weeks in women with threatened miscarriage in early pregnancy. Using a larger cohort of women from the same setting (validation cohort), we aim to assess the validity of serum progesterone <35 nmol/L with the outcome of spontaneous miscarri...

background: hyperprolactinemia is a common side effect of antipsychotic drugs that requires further investigation. the current study was designed to evaluate dose-dependent effect of chlorpromazine (cpz) on hormonal changes and uterine horn histological structure in rats. moreover, the mammary glands were analyzed to show hyperprolactinemia-induced histological changes. methods: albino wistar r...

A vaginal ring made of silicone polymers and barium sulfate, and containing 1 g of pure micronized progesterone, was developed for luteal supplementation in women undergoing cycles of in vitro fertilization (IVF). The ring, modeled on the Estring, was designed as a means of providing continuous intravaginal delivery of progesterone. Bioavailability of progesterone in the blood was demonstrated ...

OBJECTIVE In this paper the relation between progesterone levels and embryotoxic effect of serum complement was studied. DESIGN The aim of this study was to validate hypothesis that progesterone is strong inhibitor of complement embryotoxic action. SETTING We used chick embryo like an experimental model for evidence of our hypothesis. We treated chick embryos by sera acquired from healthy p...

A total number of 28 mature Barki ewes were divided into three groups according to the methods used for synchronization of estrous cycle with different drugs. Group I comprised 8 ewes received no drugs and served as control group. Group II included 10 ewes synchronized by 3 ml (15 mg) prostaglandin F2  injected i.m and repeated once after 9 days from the first injection.Group III comprised 10 ...