Chronic kidney disease (CKD) is a worldwide health problem. Serum levels of FGF23, a phosphaturic hormone, increase at the earliest stages of CKD, and have been found to be independently associated with the mortality and morbidity of CKD patients. The purpose of this study was to evaluate whether FGF23 neutralization was able to improve bone quality and osseointegration of titanium implants. Ur...

To study the mechanisms of protection against endotoxin challenge offered by antisera to smooth and rough gram-negative organisms, we have developed an assay to quantitate endotoxin neutralization based on inhibition of the Limulus amoebocyte lysate test. Dilutions of different bacterial lipopolysaccharides (LPSs) were incubated with hyperimmune rabbit sera against Escherichia coli O113, E. col...

a total of 698 blood and serum specimens from residents of 13 iranian communities were examined by plaque reduction neutralization test for antibodies to west nile virus. in general, infection rates in the north of the country were low while higher rates were observed among residents of central and southwestern iran. the highest prevalence of infection was found among residents of khuzestan pro...

HIV-1 Envelope (Env) variants are grouped into tiers by their neutralization-sensitivity phenotype. This helped to recognize that tier 1 neutralization responses can be elicited readily, but do not protect against new infections. Tier 3 viruses are the least sensitive to neutralization. Because most circulating viruses are tier 2, vaccines that elicit neutralization responses against them are n...

Serum neutralization antibody and immunoglobulin responses in 30 individuals were studied in paired serum samples which had been obtained before and 2 to 3 weeks after the administration of a recall dose of rabies tissue culture vaccine. The immune reaction consisted of a predominantly immunoglobulin G (IgG) antibody response. Also, a significant increase in neutralizing antibody titers was obs...

objective(s) herpes simplex viruses (hsvs) have widespread and ubiquitous prevalence in the human population and they have received a great deal of attention due to the range of diseases, they caused as a result of an infection. it seems that the fast and reliable diagnostic methods are needed for detecting the herpes simplex virus type 1 (hsv1) antibodies especially in patients with hsv enceph...