We have stimulated in a cultured hepatocyte system the synergistic interaction between triiodothyronine (T3) and dietary carbohydrate in the induction of malic enzyme (ME). Kinetic studies revealed that isolated hepatocytes equilibrate with media T3 within 5 min; nuclei equilibrate with media T3 by 45 min; and the half-time of T3 metabolism was 10 h in 10% serum. We demonstrated nuclear T3 rece...

Type 2 diabetes is a metabolic disorder caused by abnormal carbohydrate metabolism, and closely associated with abnormal lipid metabolism and hepato-renal dysfunction. This study investigated the anti-diabetic and hepato-renal protective properties of ziyuglycoside I (ZG01) derivative on type 2 diabetes. ZG01 was isolated from roots of Sanguisorba officinalis and chemically modified by deglycos...

Optimal dietary protocols for the athletic canine are often defined by requirements for endurance athletes that do not always translate into optimal dietary interventions for all canine athletes. Prior research studying detection dogs suggests that dietary fat sources can influence olfaction; however, as fat is added to the diet the protein calories can be diminished potentially resulting in de...

Community-based wind energy projects, with their small-scale, yet sizeable presence, provide a valuable opportunity to understand how individuals make sense of changes to their communities and to the surrounding landscape. Here, we examine the results of a 2013 mail survey of individuals residing in the vicinity of a 2 MW wind turbine that is located on the edge of the historic coastal town of ...

Everyone Exposed to Methyleugenol Whether you intend to or not, chances are you will consume approximately 6 micro-grams of methyleugenol (ME) today, according to a report in this month's issue by Dana B. Barr and colleagues of a study designed to measure ME in human blood _ serum [EHP 108:323-328]. ME is a compound that occurs naturally in a variety of spices and herbs, including clove oil, nu...

Everyone Exposed to Methyleugenol Whether you intend to or not, chances are you will consume approximately 6 micro-grams of methyleugenol (ME) today, according to a report in this month's issue by Dana B. Barr and colleagues of a study designed to measure ME in human blood _ serum [EHP 108:323-328]. ME is a compound that occurs naturally in a variety of spices and herbs, including clove oil, nu...

461 base used for the original analysis is predominantly that seen in normal patients, while the critical interpretation is the sick patient. This reviewer, for example, recently saw a liver with extensive metastases proven to be over 4700 g at necropsy (3 times normal weight) measured as normal approximately 2 weeks before death by the author's techniques in the author's nuclear facility. It w...

background and objectives: acantholimon bracteatum (girard) boiss (plumbaginaceae) is used in variety of diseases including hepatic ailments in the west regions of iran. in the present study, the hepatoprotective effect of the methanol extract (me) of a. bracteatum on formaldehyde (fa) induced liver injury has been investigated in adult male mice. methods: fifty six adult male mice were divided...

Zearalenone T-2 toxin Table I. Mycotoxins currently of most concern never be fully understood since laboratory studies, where interacting variables are of necessity limited, can only approximate the infinite number of variables manifested in nature, e.g., the chemical composition of the commodity, the complex interactions of the microbial flora, oxygen availability, presence or absence of herbi...