Early post-endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis (PEP) prediction may allow safe same-day outpatients discharge after ERCP and earlier proper management. This study aimed to assess the usefulness of the 4-hour post-ERCP serum amylase and lipase levels for PEP early prediction and to investigate predictive cut-off values for 4-hour post-ERCP serum amylase and lipase ...

Macroamylasemia is a condition of elevated serum amylase levels in which normal serum amylase form a complex with high molecular weight proteins such as immunoglobulins. This is a case report on a patient with macroamylasemia following acute asthmatic bronchitis. A 5-year-old male with cerebral palsy and developmental retardation was admitted to our hospital because of high fever and severe cou...

HE CHOICE OF RAPID METHODS for estimation of serum amylase activity is limited (1). Such methods depend upon the change in color of starch with iodine brought about by splitting of the starch by the enzyme. it is often difficult to establish an end point visually by this reaction in partially digested starch solutions, especially by those whose experience with the method is limited. Furthermore...

129 Elevations in serum levels of pancreatic enzymes are usually in the range of 14–80% in intensive care unit (ICU) patients who have no prior pancreatic pathology. 1,2 Although most of these patients do not develop clinical pancreatitis, pancreatic damage associated with elevated pancreatic enzymes is present. It is difficult to assess the clinical symptoms and signs of acute pancre-atitis in...

We describe a family of 32 subjects, including two healthy siblings without detectable pancreatic amylase in serum and five healthy relatives (one of them a sister) exhibiting subnormal pancreatic amylase activities. Comparisons of immunoreactive amylase concentrations with the corresponding amylase activities may justify the assumption of a "silent" Amy-2 allelic variant.

The serum levels of some pancreatic enzymes have been reported to be affected by age and gender. Currently, serum total amylase, pancreatic isoamylase (P-amylase) , lipase , trypsin (ogen) , pancreatic phospholipase Az (PLA* ) , and elastase I are utilized in diagnosing pancreatic diseases. We here compared age and gender-related alterations of these six pancreatic enzymes in healthy subjects t...

Macroamylasemia is a condition of persistent, elevated serum amylase activity with no apparent clinical symptoms of a pancreatic disorder. In Korea, however, no such case has been reported to date. We report a case of a 17-year-old female diagnosed with macroamylasemia and acute appendicitis. One day earlier, she developed epigastric and right lower quadrant abdominal pain. She was characterize...

Macroamylasemia results from the complexing of serum a-amylase (EC 3.2.1.1;a-1,4-glucan 4-glucanohydrolase) to a high-molecular-weight protein or proteins (macroamylase) and is characterized by hyperamylasemia and low urinary amylase clearance, associated with normal renal function. Recently a simplified detection method has been described for macroamylasemia, in which a small column of Sephade...

Isolated blunt pancreatic injuries are rare. Diagnosis is often delayed due to minimal symptoms and signs. Elevated serum amylase or lipase levels on routine pre-operative laboratory investigations makes injury highly likely. Contrast Enhanced CT scan usually confirmatory. We reporting two patients who presented with abdominal trauma, haemodynamically stable, epigastric tenderness. Pre-admissio...

A 60-year-old woman was diagnosed with metastatic pulmonary adenocarcinoma (c-stage IV) with an L858R point mutation in the gene encoding epidermal growth factor receptor (EGFR). Serum amylase levels were elevated (1,531 IU/L) with the salivary-type enzyme dominating. First-line chemotherapy using carboplatin plus paclitaxel reduced serum amylase levels, although second-line gefitinib eventuall...