Sepsis is the most common factor leading to the acute respiratory distress syndrome (ARDS) and is associated with the highest mortality rate. It has been suggested that the pulmonary surfactant system is altered and contributes to the lung dysfunction associated with ARDS. The objective of this study was to characterize the lung injury, specifically the endogenous surfactant system in septic ad...

conclusions children with chd are at risk of severe complications with the involvement of other organs. long-term febrile illness should be taken seriously in these children. they need hospitalization and careful evaluation. case presentation a 6-year-old girl with a ventricular septal defect (vsd) was presented. echocardiography revealed large vegetation in the right ventricular outflow tract ...

Liu, Shu Fang, and Asrar B. Malik. NFB activation as a pathological mechanism of septic shock and inflammation. Am J Physiol Lung Cell Mol Physiol 290: L622–L645, 2006; doi:10.1152/ajplung.00477.2005.—The pathophysiology of sepsis and septic shock involves complex cytokine and inflammatory mediator networks. NFB activation is a central event leading to the activation of these networks. The role...

Liu, Shu Fang, and Asrar B. Malik. NFB activation as a pathological mechanism of septic shock and inflammation. Am J Physiol Lung Cell Mol Physiol 290: L622–L645, 2006; doi:10.1152/ajplung.00477.2005.—The pathophysiology of sepsis and septic shock involves complex cytokine and inflammatory mediator networks. NFB activation is a central event leading to the activation of these networks. The role...

  Background   Septic arthritis is an acute infection of the joint space and a pediatric emergency. Delay in proper diagnosis and treatment, while prolonging the course of treatment, can have serious complications. The present study aimed to assess the clinical and laboratory profile of septic arthritis among patients hospitalized in the pediatric war...

septic shock continues to be one of the leading causes of death in the intensive care units. when the shock state persists after adequate fluid resuscitation,  vasopressor therapy is required to improve and maintain adequate tissue/organ  perfusion in an attempt to improve survival and prevent the development of multiple organ dysfunction and failure. various studies have suggested that exogeno...

purpose: despite discovering new antibiotics, mortality due to septic shock has remained high.   this research has examined the effect of selenase in patients with septic shock admitted to the   intensive care unit (icu) of a hospital in tehran.   materials and methods: this double-blind clinical trial was done on 80 participants (40 case   and 40 control) who were admitted to the icu with sept...

severe sepsis and septic shock are major problems as the result of high rates morbidity andmortality in intensive care units (icus). in the presence of septic shock, each hour of delay inthe administration of effective antibiotics is associated with a measurable increase in mortality.aminoglycosides are effective broad-spectrum antibiotics that are commonly used in icus forthe treatment of life...

background : an accurate and prompt diagnosis of bacterial arthritis is essential for earlier treatment and a good outcome. superantigens produced by staph. aureus are among the most lethal toxins. the paper objective was identification of common bacterial antigens and s.aureus superantigens in synovial fluid (sf) of children with negative culture and direct smear for other bacteria except for ...

mycotic aneurysm could be divided into three types according to their etiology: septic-embolic, cryptogenic and traumatic type. during the period from 1972 to 1974 two cases of mycotic aneurysms have been seen at the ohio valley medical center - one following a sub acute bacterial endocarditic and another one was two years following surgery for aortofemoral bypass graft. the clinical course of ...