BACKGROUND Use of psychotropic and sedative drugs has been associated with impaired muscle strength. Muscle weakness predicts important outcomes for older people including functional disability and mortality. The objective of this study was to investigate if the use of drugs with sedative properties is associated with poorer muscle strength. METHODS Seven-hundred community-dwelling participan...

In the present work sedative and hypnotic effects of aqueous extract of Aloe vera in rats have been investigated. In order to evaluate the overall hypnotic effects of the Aloe vera extract, open field and loss of righting reflex tests were primarily used. The sedative and hypnotic effects of the extract were then confirmed by detection of remarkable raise in the total sleeping time through anal...

Introduction and Objectives. Preanesthetic medication may reduce the risks of adverse psychological and physiological sequela of induction of anesthesia in children. Administration of premedication by sublingual route may provide the best compromise, that is, relatively rapid absorption without causing pain. In this study, we compared sedative and anxiolytic effects of midazolam and buprenorphi...

In the present work sedative and hypnotic effects of aqueous extract of Aloe vera in rats have been investigated. In order to evaluate the overall hypnotic effects of the Aloe vera extract, open field and loss of righting reflex tests were primarily used. The sedative and hypnotic effects of the extract were then confirmed by detection of remarkable raise in the total sleeping time through anal...

introduction : factors like preparing pediatric patients for anesthesia and surgery, separating them from parents, peculiarity of operation rooms and painful procedures such as injection usually produce anxiety and lack of cooperation in children. oral premedication with a sedative, anti-anxiety drug which has no major side effects can response to these challenges. materials and methods : in th...

BACKGROUND Older people with dementia may be particularly susceptible to cognitive impairment associated with anticholinergic and sedative medicines. This impairment may be misattributed to the disease process itself. OBJECTIVE This review examines clinical considerations associated with using anticholinergic and sedative medicines in people with dementia or incipient cognitive impairment. It...

In spite of tremendous advances in medical science, sleep has not been understood completely. The causes for many of parasomnias are still not evident. Even then these parasomnias are treated with different drugs, one of the major groups among them being sedative hypnotics. The use of sedative hypnotics are always associated with adverse effect, and there is many a times loss of the normal slee...

Withania somnifera Dunal commonly known as Asgandh or Ashvaganadha is one of the most potent aphrodisiacs used in traditional systems of medicine. It is common herb found throughout the dried and subtropical parts of India. The root and leaves of plants are used for medicinal purposes. In traditional systems of medicine particularly Ayurveda and Unani the plant is thought to possess anti-inflam...