Culcitiolides E-J (1-6), six new eremophilane-type sesquiterpenes, were isolated from the stem of Senecio culcitioides SCH. BIP. (Asteraceae). The structures were determined by detailed NMR spectral analysis. The inhibitory activities of these compounds against nuclear factor κB (NF-κB)-dependent gene expression were assessed. Culcitiolides E, H, and I potently inhibited NF-κB-induced gene expr...

The present study aimed to investigate the acute antihyperglycemic effects of four different solvent extracts (Petroleum ether, acetone, absolute ethanol and water) of two plants: Cleome rutidosperma (leaves) and Senecio biafrae (root) in STZ-induced diabetic mice and their in vitro antioxidant activities as well as their phytoconstituents. A single administration of the extracts at a dose of 5...

Nymphs of Stenoscepa sp. feed on leaves of the Ni hyperaccumulator Berkheya coddii at serpentine sites in Mpumalanga Province, South Africa. These sites contain Ni hyperaccumulators, Ni accumulators, and plants with Ni concentrations in the normal range. We conducted studies to: (i) determine the whole-body metal concentration of nymphs (including those starved to empty their guts); (ii) compar...

2827 Heterogeneity of Strain R Avian (Erythro blastosis) Virus. 2852 Pharmacological Studies of the Antitumor Agent 6-Methylthiopurine Ribonucleoside. 2863 Cytolytic Effect of 6-Hydroxydopamine on Neuroblastoma Cells. 2881 Development of Hepatic Tumors in Rats following Ingestion of Senecio longiobus. 2898 Stimulatory Effect of Benzo(a)pyrene and Phenobarbital Pretreatment on the Biliary Ex cre...

The aim of our study was to investigate the intrinsic diversity of genus based on chemical composition of natural extracts of Cacalia, Dracocephalum, Jatropha, Saussurea and Senecio. Four rarefaction approaches (richness, Shannon’s entropy, Simpson’s diversity, and max-entropy) were implemented as an algorithm and run 10,000 times. Our results showed similar patterns of richness in natural comp...

Interspecific hybridization is an important mechanism of speciation in higher plants. In flowering plants, hybrid speciation is usually associated with polyploidy (allopolyploidy), but hybrid speciation without genome duplication (homoploid hybrid speciation) is also possible, although it is more difficult to detect. The combination of divergent genomes within a hybrid can result in profound ch...