Organochlorine chemical residues and elemental contaminants were measured in northern pike (Esox lucius), longnose sucker (Catostomus catostomus), and burbot (Lota lota) from 10 sites in the Yukon River Basin (YRB) during 2002. Contaminant concentrations were compared to historical YRB data and to toxicity thresholds for fish and piscivorous wildlife from the scientific literature. A risk analy...

To establish guidelines for the selenium supplementation in radiotherapy we assessed the benefits and risks of selenium supplementation in radiotherapy. Clinical studies on the use of selenium in radiotherapy were searched in the PubMed electronic database in January 2013. Sixteen clinical studies were identified among the 167 articles selected in the initial search. Ten articles were observati...

BACKGROUND Elemental selenium nanoparticles have emerged as a novel selenium source with the advantage of reduced risk of selenium toxicity. The present work investigated whether heat treatment affects the size, structure, and bioactivity of selenium nanoparticles. METHODS AND RESULTS After a one-hour incubation of solution containing 80 nm selenium particles in a 90°C water bath, the nanopar...

There are several manners in which selenium may express its toxicity: (1) an important mechanism appears to involve the formation of CH(3)Se(minus sign) which either enters a redox cycle and generates superoxide and oxidative stress, or forms free radicals that bind to and inhibit important enzymes and proteins. (2) Excess selenium as selenocysteine results in inhibition of selenium methylation...

Aflatoxin B1 (AFB1), among other aflatoxins of the aflatoxin family, is the most carcinogenic and hazardous mycotoxin to animals and human beings with very high potency leading to aflatoxicosis. Selenium is an essential trace mineral possessing powerful antioxidant functions. Selenium is widely reported as an effective antioxidant against aflatoxicosis. By preventing oxidative liver damage, sup...

The present study aimed to assess the protective role of selenium against cadmium induced hepatotoxicity. The rats were given subcutaneous doses of 1mg/Kg body weight of either normal saline or cadmium chloride or sodium selenite or cadmium chloride plus sodium selenite on alternate days for four weeks. The results showed that cadmium treatment increased hepatic levels of lipid peroxidation, DN...

Selenium is one of the most interesting of all nutrients. It was first known for its toxicity and was then discovered to be an essential nutrient. The power of its antioxidant activity has been widely acclaimed. The importance of selenium in immune response and as an anticarcinogen has recently received a great amount of attention. In fact, selenium has been claimed to have a protective role in...

Introduction Selenium is an essential element to human health at low levels (2080 μg/L), but becomes toxic at elevated levels. Selenium exists in different forms that determine its toxicity and bioavailability. Current research is now focusing on the determination of individual selenium species or seleniumcontaining compounds. This can be done using ICP-MS as a selenium-specific detector for a ...

Introduction Selenium (Se) is a group VI element with chemical properties very similar to those of sulfur, it has been demonstrated as an essential element for ruminants. Selenium is required to prevent deficiency diseases such as white muscle disease, maintain growth rates of young animals and promote reproductive performance. Camel sensitivity to trace element imbalances has been reported (Fa...