mood, one might predict that normal individuals treated with serotonin reuptake blockers would experience euFluoxetine and the Serotonin Model for Depression phoria, and that dietary serotonin depletion would inFluoxetine (a.k.a. Prozac) is well known for its ability to duce depression. In fact, these manipulations of serototreat clinical depression, one of the most prevalent of nin levels have...

Depression and sexual dysfunction are both common in the general population. When they co-exist they have the potential to impact negatively on each other in a bidirectional manner. Medication used to treat depression may cause additional problems with the sexual response cycle; although no drug is completely innocent, serotonergic agents such as selective serotonin reuptake inhibitors (SSRIs) ...

Depression and sexual dysfunction are both common in the general population. When they co-exist they have the potential to impact negatively on each other in a bidirectional manner. Medication used to treat depression may cause additional problems with the sexual response cycle; although no drug is completely innocent, serotonergic agents such as selective serotonin reuptake inhibitors (SSRIs) ...

SSRIs are chemically distinct from traditional antidepressants such as tricyclic, tetracyclic, and monoamine oxidase inhibitors, but they share the same mechanism of action in that selectively potently inhibit serotonin neuronal reuptake while having no or very little effect on norepinephrine, acetylcholine, histamine reuptake. As a result, when compared to other tricyclic tetracyclic antidepre...

PURPOSE To describe the risk of early- and late-onset preeclampsia across pregnancies exposed to antidepressants and to evaluate the impact of timing and length of gestational exposure to antidepressants, particularly selective serotonin reuptake inhibitors (SSRIs), on preeclampsia. METHODS The Norwegian Mother and Child Cohort, a prospective population-based study, and the Medical Birth Regi...

neuroleptic malignant syndrome (nms) is a rare fatal medical complication that occurs as a result of dopaminergic receptor blockage in the caudate at the termination of the nigrostriatal pathways (1), and may occur at any time following consumption of dopamine antagonists. this disorder also occurs in cases of sudden discontinuation of dopamine agonists and antagonists (2,3). some studies have ...

(Letter to the Editor) SIR, We read with great interest the report by Coleiro et al. [1] describing a pilot study on the tolerability and efficiency of fluoxetine for the treatment of Raynaud's phenomenon. This study confirmed previous case reports suggesting the usefulness of selective serotonin reuptake inhibitors (SSRIs) in the management of Raynaud's phenomenon [2, 3]. Here we describe for ...

A frontal lobe syndrome has previously been reported in adults treated with selective serotonin reuptake inhibitors (SSRIs), but not in children. Five typical cases of apathy and lack of motivation, one accompanied by disinhibition, are described in a child and four adolescents. Symptoms were dose related and reversible. The subtlety of symptoms, lack of insight in patients, disabling effects, ...