We present here an account of two infant sisters suffering from a congenital and, probably, inherited disease, the chief features of which were epilepsy, cataracts, renal tubular necrosis and an encephalopathy comprising micrencephaly, lack of myelination and cerebellar dysplasia. The condition resembles the so-called Marinesco-Sjogren syndrome and also the oculo-cerebro-renal (Lowe's) syndrome...

Bertie L., aet. 6, has been noticed by his parents never to shed tears from the right eye. On several occasions I have seen him crying, and though the tears flowed copiously from the left eye, they never came from the right. That they were not secreted was demonstrated by drawing away the lower lid from the globe, when there was no accumulation of tears in the cul-de-sac thus formed. In the lef...

Multiagent chemotherapy as neoadjuvant treatment for multifocal intraocular retinoblastoma. Ophthalmology. 2001;108:2106-2115. 9. Madreperla SA, Hungerford JL, Cooling RJ, Sullivan P, Gregor Z. Repair of late retinal detachment after successful treatment of retinoblastoma. Retina. 2000;20:28-32. 10. Baumal CR, Shields CL, Shields JA, Tasman WS. Surgical repair of rhegmatogenous retinal detachme...