In the article by Mohanan Nair et al, “A Case of Rheumatic Fibrinous Pericarditis,” which appeared in the December 2016 issue of the journal (Circ Cardiovasc Imaging. 2016;9:e005399. DOI: 10.1161/CIRCIMAGING.116.005399), a correction is needed. On page 1, the second sentence should read: “He provided history of rheumatic fever in the past and was on intramuscular benzathine penicillin prophylax...

The World Health Organization endorses registries as a valuable adjunct to managing rheumatic heart disease (RHD). This study evaluated the management of New Zealand RHD Registry patients from 2010 2019 and alignment Heart Foundation Guidelines. A retrospective audit was undertaken 150 in Tāmaki Makaurau, randomly selected Registry, with review frequency specialist follow-up echocardiograms, do...

Post-streptococcal sequelae, especially acute rheumatic fever/rheumatic heart disease continue to occur in significant proportions in many parts of the world. Despite several attempts with various intervention strategies, little success has been achieved in the control of acute rheumatic fever/rheumatic heart disease in India. The success of the control programmes depends upon timely primary pr...

Editorials 559 Syphilis is unique among sexually transmitted diseases in that it remains curable (with minimal reports of resistance) with a single dose of penicillin , formulated for this purpose as long-acting benzathine penicillin. Pregnant women with untreated syphilis experience adverse birth outcomes in over half of untreated pregnancies. These outcomes include stillbirth, organ deformiti...

Latar belakang. Infeksi Streptococcus yang memicu demam rematik dapat mendasari terjadinya penyakit jantung didapat pada anak. Demam dicegah baik dari pencegahan primordial, primer, dan sekunder. Anak dengan keparahan penyakitnya mencegah infeksi berulang atau Pencegahan sekunder dianjurkan oleh World Health Organization (WHO) adalah pemberian Benzathine Penicillin G (BPG) setiap 3 – 4 minggu. ...

Roxithromycin (RU 965), a new macrolide antibiotic, was shown to be effective for therapy of active syphilis in rabbits. Dark-field-positive lesions were produced in adult male rabbits by intradermal inoculation of approximately 10(6) Treponema pallidum organisms at each of 11 sites. Beginning 7 days after infection, six animals per group were treated with benzathine penicillin G (200,000 U, in...

Benzathine Penicillin G (BPG) is commonly used for treatment of penicillin-susceptible infections and secondary prevention of rheumatic fever. Death following administration of BPG is extremely rare-only a handful of cases have been described in the literature since the 1950's. In this case series from Israel and Switzerland, we describe nine cases of serious adverse reactions-six fatal reactio...

Leucoderma syphiliticum (LS), originally described as syphilide pigmentaire, encompasses a spectrum of dyschromic lesions that emerge during the course of secondary syphilis. Very few case reports are available in modern biomedical databases. We present the case of a 57-year-old HIV-infected male patient who presented with several round to oval, non-scaling, slightly raised and well-demarcated ...