tion, and the lipidized DF, with a homogeneous yellowish area.3,6 Although initially considered rare, sebaceous structures are identified in more than 15% of DFs,4,5,7 even in multiple forms.8 This finding is typical in lesions localized in the anatomical area of the shoulder (shoulder, proximal region of the arm, upper back and deltoid region), being observed in more than 40% of these cases, p...

Figure Legend: Figure 1 Oral mucosa, Gingiva Ectopic tissue, Sebaceous gland in male F344/N rat from a chronic study. There are clusters of sebaceous glands in the gingiva. Figure 2 Oral mucosa, Gingiva Ectopic tissue, Sebaceous gland in male F344/N rat from a chronic study (higher magnification of Figure 1). The clusters of sebaceous glands in the gingiva are adjacent to a dilated duct. Figure...

tion, and the lipidized DF, with a homogeneous yellowish area.3,6 Although initially considered rare, sebaceous structures are identified in more than 15% of DFs,4,5,7 even in multiple forms.8 This finding is typical in lesions localized in the anatomical area of the shoulder (shoulder, proximal region of the arm, upper back and deltoid region), being observed in more than 40% of these cases, p...

CNS: central nervous system IHC: immunohistochemistry MMR: mismatch repair MTS: Muir-Torre syndrome M uir-Torre syndrome (MTS) is an autosomal-dominant variant of Lynch hereditary cancer syndrome. MTS is defined by sebaceous neoplasms occurring in association with 1 or more internal malignancies. The sebaceous neoplasms that characterize MTS are rare among the general population and include seb...

Ever since Sir James Paget first described the disease of the nipple named after him and remarked that he had seen a lesion clinically resembling it on the glans penis, followed by cancer, reputed cases of extramammary Paget’s disease have been sporadically reported and their nature discussed. The debate has been ancillary to the related question of the nature of Paget’s disease, which is still...

A BENIGN calcifying epithelioma is a subcutaneous tumour, first described by Malherbe and Chenantais (1880), who called it l'epitheliome calcifie des glandes sebacees. Malherbe (1881, 1905) added more details, but only four examples of such tumours have been reported in the ophthalmic literature (Ashton, 1951; Kornblueth and Liban, 1955). Histological examination of material from the Radcliffe ...

BACKGROUND Ocular sebaceous carcinoma is an uncommon, aggressive ocular neoplasm with potential for regional and distant metastasis. CASE PRESENTATION A 77-year-old woman was found to have a solitary pulmonary lesion 6 years after the initial treatment of sebaceous carcinoma of the eyelid. Video-assisted lung wedge resection of an undetermined pulmonary nodule was carried out successfully. Mi...

Sebaceous adenoma of the salivary gland is a rare tumor comprising 0.1% of all salivary gland neoplasms and less than 0.5% of salivary adenomas. Histologically, sebaceous adenomas are benign neoplasms consisting of sebaceous cells arranged in nests forming acinar and duct-like structures. Oncocytic metaplasia may also occur in some areas. We describe a case of sebaceous adenoma in the submandib...

A recent large-scale retrospective study has revealed that the frequency and aggressiveness of extraocular sebaceous carcinoma is comparable with that of the periocular counterpart (1) and a signiflcant number of extraocular sebaceous carcinomas show regional and widespread métastases (2). However, sentinel lymph node (SLN) biopsy has seldom been used for identifying regional nodal metastasis i...

Mitochondria are not difficult to demonstrate in sebaceous cells. Yet, they are only briefly described in the literature. Nicholas et al (4) believed that mitochondria in sebaceous cells undergo a direct transformation into lipid droplets. In the sebaceous glands of the mouse the mitochondria are said to increase in number at the beginning of lipid storage, to decrease during sebaceous transfor...