PURPOSE Scrophularia variegata M. Beib. (Scrophulariaceae) is an Iranian medicinal plant which is used for various inflammatory disorders in traditional medicine. In this study we evaluated the anti-cancer and cytotoxic effects of the Scrophularia variegata (S. variegata) ethanolic extract on the human breast cancer cell line. METHODS The cytotoxicity effect of the extract on MCF-7 cells was ...

The current study was assigned to evaluate the total phenol, total flavonoid content (TPC, TFC) and antioxidant properties of extracts from the aerial parts of Scrophularia frigida (S. frigida). Extracts were also tested by preliminary phytochemical screening as well as cytotoxic activity against Artemia salina, MCF-7 (human breast carcinoma) and SW-480 (colon carcinoma) and L-929 (normal) cell...

In China, Scrophularia ningpoensis Hemsl (Scrophulariaceae) has been cultivated for many years; however, the effects of drought on the content of secondary metabolites in Radix Scrophulariaceae are still unknown. The study investigated the medicinal components of S. ningpoensis including harpagoside, aucubin, catalpol, harpagide, and cinnamic acid in relation to drought stress. Three ecotypes o...

Effective neuroblastoma (NB) treatments are still limited despite treatment options available today. Therefore, this study attempted to identify novel plant extracts that have anticancer effects. Cytotoxicity and increased intracellular calcium levels were determined using the Sulforhodamine B (SRB) assay and Fluo4-AM (acetoxymethyl) staining and fluorescence microscopy in NB cells in order to ...

As part of the ongoing study some genera Caryophyllaceae and preparation their treatments for new edition Flora Argentina, notes about members this family are presented. Two species (Petrorhagia prolifera Scleranthus polycarpos) reported first time Argentina. Sixteen names here lectotypified: Arenaria achalensis, A. alsinoides, andicola, bisculca, lanuginosa var. diffusa, ensifolia, megalantha,...