background: cystic echinococcosis (ce), a zoonotic parasitic infection caused by the metacestode (larvae) stage of dog tapeworm echinococcus granulosus and recognized as a major economic and public health concern in the world. this study aimed to investigate the in vitro scolicidal effect of methanolic extract of berberis vulgaris l. roots and its main compound, berberine against protoscoleces ...

background: this investigation aimed to evaluate the in vitro scolicidal effects of pistacia khinjuk methanolic extract against protoscoleces of hydatid cysts and its acute toxicity in mice nmri model. methods: protoscoleces were aseptically extracted from sheep livers having hydatid cysts. various concentrations of the essential oil (12.5- 100 mg/ml) were used for 10 to 60 min. viability of pr...

Objective(s): Nanoparticles (NPs) are particles with the size range approximately from 1 to 100 nanometers that are made in different shapes. Nanotechnology is an emerging technology that expected to open some new opportunities in order to destroy and control of microorganisms using of materials and systems at the scale of the atom. Echinococcus granulosus is the agent of cystic echinococcosis ...

Hydatidosis is characterized by the long-term coexistence of larva Echinococcus granulosus and its host without effective rejection. Previous studies demonstrated nitric oxide (NO) production (in vivo and in vitro) during hydatidosis. In this study, we investigated the direct in vitro effects of NO species: nitrite (NO(2) (-)), nitrate (NO(3) (-)) and peroxynitrite (ONOO(-)) on protoscolices (P...