Microstructured optical fibers containing alkali halide scintillation materials of CsI(Na), CsI(Tl), and NaI(Tl) are presented. The scintillation materials are grown inside the microstructured fibers using a modified BridgmanStockbarger technique. The x-ray photon counts of these fibers, with and without an aluminum film coating are compared to the output of a collimated CdTe solid state detect...

9 The cross section for photoneutron production in Be at energies of 1. 692, 1. 720, and 1. 78 Mev has been investigated using radioisotope gamma-ray sources. Neutron counting was by manganous sulfate bath and a long counter. Gamma-ray counting was by a scintillation spectrometer consisting of a Nal(Tl) scintillation crystal and a 256-channel pulse^height analyzer. The following results were ob...

The microplate format has become a standard for many biological assays such as high throughput screening for drug discovery and radioimmunoassays. Productivity with these high volume procedures has been limited by the amount of sample handling required and low sample counting throughput. Now, however, microplate assays can be efficiently counted in microplates with the Packard TopCount Micropla...

The TopCount Microplate Scintillation and Luminescence Counter is capable of analyzing radiolabeled microplate samples in a wide variety of formats using liquid and solid scintillation counting techniques. Quench is a common interference in scintillation counting which reduces the sample’s apparent activity. In most applications, the level of quench is constant; hence, it need not be considered...

14CO2 capture is commonly used to evaluate the cellular oxidation rate of respiratory substrates. A modification of the established 14CO2-capture method was developed that enables the use of cells in adherent culture and easy analysis of multiple samples under different culture conditions. The use of commercially available culture and filter plates designed for use in a multiplate scintillation...

In a two-compartment scintillation vial, suspensions of bacteria were cultured with 1 muCi of [U-14C] glucose and the released 14C02 was measured continuously, cumulatively, and automatically in a liquid-scintillation counter modified to maintain sample temperature at 37 degrees C. We could follow the metabolism of bacterial populations through their early phase of exponential growth with good ...

The TopCount Microplate Scintillation and Luminescence Counter has been widely used in biopharmaceutical assays involving both radionuclide and luminescence measurement. A new feature allows the use of TopCount for measuring a high energy beta emitter such as P by Cerenkov counting, a well-known measurement technique that has the main advantage of not requiring the addition of scintillation coc...