The purpose of this study was to compare the topical anti-inflammatory effects of the nonselective cyclooxygenase (COX) inhibitor, ketorolac, with the selective COX-2 inhibitor, nimesulide, in an animal model of dry eye in albino rabbits. All animals were examined by the Schirmer test, tear break-up time (TBUT) and fluorescein corneal staining test. Dry eye model showed significant reduction in...

Objectives A 12-year-old girl was admitted to our hospital due to large erythematosus lesions on pretibial region that has been seen for three years. These lesions were started with hyperemic, tender and nodular forms then changed to a dark brown macular coloration and persists afterward. She did not suffer from dry mouth or eye. However, when the medical history was examined carefully, she poi...

PURPOSE An oil in water emulsion of 0.01% all-trans-retinoic acid (tretinoin) was prepared and clinically evaluated in dry eye patients. METHODS The ophthalmic emulsion consisted of 10% of arachis oil and 90% of the hydrogel of Carbopol 940. To evaluate retinoic acid emulsion clinically, a placebo-controlled, open-labeled, randomized study was performed with 22 dry-eye patients. Symptoms were...

PURPOSE To evaluate whether alterations in plasma vitamin A and E levels in patients with psoriasis have an effect on tear film changes. METHODS Sixty-two eyes of 31 patients with psoriasis vulgaris (Group A) and 74 eyes of 37 age- and gender-matched control subjects (Group B) were included in the study. Ocular and medical histories and dietary habits were obtained from each patient. The tear...

PURPOSE We measured tear film parameters, including the morphology and function of meibomian glands, in junior high school students at 15 years of age. METHODS A total of 111 eyes of 111 students (56 males and 55 females) were enrolled in the study. The ocular symptom score (0-14), after-school study time, lipid layer thickness (LLT) of the tear film, partial blink rate, lid margin abnormalit...

Introduction: The aim of this study was to eva-luate the salivation flow rate objectively using Schirmer test and mouth dryness and other con‌sequences subjectively by distributing question‌naires to patients receiving head and neck radio‌therapy. Materials and Methods: In this descriptive study that was carried out at Imam Khomeini hospital, Tehran, Iran, the saliva flow rate of 33 patients r...

OBJECTIVES To investigate tear ferning (TF) test repeatability between sessions by observing changes in the tear fern pattern during the day. METHODS Twenty-three healthy young adults (15 men and 8 women), ranging in age from 20 to 32 years (mean ± SD: 22.9 ± 3.3 years) without signs or symptoms of dry eye disease, ocular disease, or contact lens wear were enrolled in the study. Schirmer I, t...

Purpose. To evaluate the relationship between corneal and conjunctival epithelium thickness and ocular surface clinical tests in dry eye disease (DED) patients. Patients and Methods. Fifty-four patients with DED and 32 control subjects were included. Each patient underwent an ocular surface evaluation using the ocular surface disease index (OSDI), tear film break-up time (TBUT), corneal and con...

Purpose: Not much attention is given to evaluation of ocular surface abnormalities in diabetics. This study has been carried out evaluate factors like age, sex, duration diabetes causing dry eye type 2 diabetics along with tear film stability using various tests Schirmers test and Tear break up time. Materials Methods: In this observational cross-sectional study, 50 patients were examined, who ...