The genus Salvia is a valuable origin of structurally diverse terpenoids. In a project directed at structurally interesting bioactive metabolites from Iranian Salvia species, we studied Salvia reuterana. Two new labdane diterpene, 6β,14α-dihydroxy-15-acetoxysclareol (1), and 14α,15- dihydroxy sclareol (2), were isolated from the aerial part of the plant. Their structures were established mainly...

Background and objectives: Salvia species are important because of their medicinal, traditional and economical uses. They are used traditionally for treatment of several diseases. The genus Salvia is represented in the Iranian flora by 61 species of which, 17 are endemic.  In the present study, the phytochemical and biological effects of two Iranian Salvia species hav...

background & aim: salvia macrosiphon is one of the important species of salvia which belongs to the lamiaceae family. all 58 iranian species of salvia grow in different ecological places. the aim of this research is the investigation of morphological and anatomical characteristics of s.  macrosiphon. experimental: the above–mentioned species were collected from zavarijan and dodangeh regio...

The purpose of this study was to investigate the effect of Salvia miltiorrhiza on the production of plasminogen activator inhibitor-1(PAI-1) induced by angiotensin II (Ang II) in renal mesangial cells. Rat mesangial cells were exposed to 100 nM Ang II. Meanwhile, different concentrations of Salvia miltiorrhiza injection were added to Mesangial Cells. PAI-1 mRNA was measured by semi-quantificati...

The antimicrobial activity of three Salvia species, i.e. S. santolinifolia, S. hydrangea and S. mirzayanii, essential oils were investigated. The essential oils were obtained from the aerial parts of plants and analyzed by GC-MS. The main constituents of aforementioned species were alpha-pinene (72.4%), beta-pinene (6.6%) and limonene (5.3%); beta-caryophyllene (25.1%), 1,8-cineol (15.2%) and c...

This study documents the flavonoid constituents of seven Salvia species in Iran namely S.atropatana Bunge, S. limbata C. A. Mey, S. sclarea L., S. ceratophylla L., S. multicaulis Vahl.,S. hydrangea Dc. ex Benth., and S. eremophila Boiss. The studied species were collected fromtheir natural habitats in Iran and were analyzed for their flavonoid constituents using twodimensionalthin layer chromat...

In the course of the evaluation of the species belonging to the Section Salvia of the genus Salvia (Family Lamiaceae) the essential oil content and the composition of the species have been investigated with special respect to their neurotoxic α-, and β-thujone content. It could be established that from among the species S. lavandulifolia Vahl., S. candelabru Boiss., S. tomentosa Mill., (S. gran...

An ethnobotanical study was carried out in the Saïda region among herbalists to evaluate the use of Salvia argentea (L.), a plant species native from North Africa belonging to the Lamiaceae family. Forty-two herbalists were interviewed individually, aged between 30 and 70 years, all males, 52.38% of them having received a secondary education level and having performing their duties for more tha...

Sage (Salvia) species is known as the Functional Novel Natural Medicine, Salvia Extract are considered important for drug development, because they are reported to have Pharmacological activity in the Asia, Middle East especially China and India. For a long time Salvia has been used in traditional medicine for the relief of pain, protecting the body against oxidative stress, free radical damage...