BACKGROUND Measurement of late-night salivary cortisol concentrations is increasingly used as a screening test in suspected Cushing's syndrome. Cortisol concentrations are typically extremely low in late-night samples and discordant assay-specific reference ranges have been reported. Therefore, the aim of our study was to assess the analytical performance of the first automated cortisol immunoa...

To date, a single report has appeared on the use of salivary cortisol for adrenal function testing with a low dose ACTH, although 1 microg has become preferred as a more physiological stimulus than the commonly used 250 microg ACTH test. Our present study was aimed to obtain physiological data on changes of free salivary cortisol after 1 microg ACTH stimulation. This approach was compared with ...

It is of interest to investigate the effectiveness a mindfulness-based stress reduction program on and salivary cortisol among substance abuse patients. There were 60 drug addicts who receiving treatment at addiction centre. Samples are divided into 30 patient experimental control groups using simple random sampling approach. Salivary cortisol, pre-test biomarker, was measured used analyse resu...

Salivary cortisol is an index of plasma free cortisol and is obtained by a noninvasive procedure. We have been using salivary cortisol as a tool for physiological and diagnostic studies, among them the emergence of circadian rhythm in preterm and term infants. The salivary cortisol circadian rhythm in term and premature infants was established between 8 and 12 postnatal weeks. In the preterm in...

References 1. Ramsay DS, Lewis M. The effects of birth condition on infants’ cortisol response to stress. Pediatrics 1995;95:546–9. 2. Flinn MV, England BG. Social economics of childhood glucocorticoid stress response and health. Am J Phys Anthropol 1997;102:33–53. 3. Antonini SRR, Jorge SM, Moreira AC. The emergence of salivary cortisol circadian rhythm and its relationship to sleep activity i...

......................................................................................5 Introduction...................................................................................6 Method.......................................................................................15 Participants.........................................................................15 Design.........................

background although the link between psychological distress and altered cortisol level has been already shown; very limited information exists about this association among black youth. objectives we tested sex differences in predictive role of symptoms of anxiety during adolescence on annual decline in morning salivary cortisol levels in early adulthood among black youth. conclusions our findin...

INTRODUCTION The 'diurnal slope' of salivary cortisol has been used as a measure of stress and circadian function in a variety of reports with several detailing its association with cancer progression. The relationship of this slope, typically a negative value from high morning concentrations to low evening concentrations, to the underlying daily variation in total plasma cortisol throughout th...

BACKGROUND Uncontrollable aversive events are associated with feelings of helplessness and cortisol elevation and are suitable as a model of depression. The high comorbidity of depression and pain symptoms and the importance of controllability in both conditions are clinically well-known but empirical studies are scarce. The study investigated the relationship of pain experience, helplessness, ...

OBJECTIVE Cushing's syndrome (CS) is characterized by changes in diurnal cortisol variation and total or partial resistance to cortisol suppression by dexamethasone (DEX). Diagnosing CS is a challenge especially in childhood and requires differentiation from primary obesity. The aim was verify the efficacy of salivary cortisol in differentiating primary obesity from CS in children. SUBJECTS A...