The low-affinity glucose-phosphorylating enzyme glucokinase (GK) is the flux-limiting glucose sensor in liver and -cells of the pancreas. Furthermore, GK is also expressed in various neuroendocrine cell types. This review describes the complex network of GK regulation, which shows fundamental differences in liver and pancreatic -cells. Tissue-specific GK promoters determine a higher gene expres...

s S55 Eur J Echocardiography Abstracts Supplement, December 2006 analysed by 2 separate observers. TOE and RT-3DE images were acquired digitally on the Phillips IE33 ultrasound machine and stored for off line analysis. The RT-3DE datasets were analysed with Phillips Qlab software (version 4.0). Leaflet segments and commissures were displayed in short axis en-face and long axis views. Echocardio...

The Sindbis-group alphavirus S.A.AR86 encodes a threonine at nonstructural protein 1 (nsP1) 538 that is associated with neurovirulence in adult mice. Mutation of the nsP1 538 Thr to the consensus Ile found in nonneurovirulent Sindbis-group alphaviruses attenuates S.A.AR86 for adult mouse neurovirulence, while introduction of Thr at position 538 in a nonneurovirulent Sindbis virus background con...

1. Our research is a case study where specific forensics tools and mobile devices were only used to illustrate the utility of a formal method called decision analysis. To the best of our knowledge such a technique for tool testing has not been published in a peer-reviewed journal in the past. 2. Decision theory and analysis draw on a very serious body of work from probability, utility, and epis...

Stellar orbits at the Galactic Center provide a very clean probe of gravitational potential supermassive black hole. They can be studied with unique precision, beyond confusion limit single telescope, near-infrared interferometer GRAVITY. Imaging is essential to search field for faint, unknown stars on short which potentially could constrain hole spin. Furthermore, it provides starting point as...

Dasht-e-Arjan is a northeast trending graben located 65 km west of Shiraz. It was formed along active segments of the Korrehbas fault, perpendicularly to the Shahnesh in and Salamati anticlines. Oriented sampling from bordering fault planes and striations was carried out to evaluate the relative amounts of paleostress/strain needed to form the graben. Measurements of e-twins and c-axis of calci...

grapevine is among some of the most important horticultural crops in the world and as well in iran. since last century attempts have been made throughout the world to improve grapes. research in grape breeding for the purpose of improving table grape as well as raisin traits has started since 1996 in iran with crossing some selected seedless (askary, yaghoti, bidane sefid (sultana) and bidane g...