نتایج جستجو برای: s lymphoma nhl

تعداد نتایج: 809197  

2012
Naohiko KOIDE Shinichi MIYAGAWA

We report 5 cases of non-Hodgkin lymphoma of the small intestine (S-NHL)treated with emergency operation.These cases showed three reasons for emergency operation:[1]massive hemorrhage with shock before diagnosis of S-NHL(Case 1),[2]obstruction of the small intestine before and during chemotherapeutic treatment for S-NHL (Cases 2 and 3),and[3]spontaneous perforation with peritonitis before diagn...

Journal: :British journal of haematology 2016
Ross Pinkerton Mitchell S Cairo Finbarr E Cotter

The 5th International Symposium on Childhood, Adolescent and Young Adult (CAYA) Non-Hodgkin Lymphoma (NHL) was held in Varese, Italy, from 21-25 October 2015. This review represents a summary of the scientific sessions of this international symposium including childhood, adolescent and young adult (AYA) NHL in countries with limited socio-economic resources, AYA NHL, anaplastic large cell lymph...

Journal: :Blood 1992
P P Brons J M Raemaekers M J Bogman P E van Erp J B Boezeman A H Pennings H M Wessels C Haanen

Cell cycle kinetics of malignant lymphoma were investigated using in vivo labeling with iododeoxyuridine (IdUrd) and subsequent flow cytometry (FCM) of IdUrd/DNA and Ki-67/DNA. This approach provides an extensive cell kinetic profile from only one single tumor biopsy, including data upon the percentage of S-phase cells, the IdUrd labeling index (LI), Ki-67-derived growth fraction, duration of t...

2013
Katia Beider Elena Ribakovsky Michal Abraham Hanna Wald Lola Weiss Evgenia Rosenberg Eithan Galun Abraham Avigdor Orly Eizenberg Amnon Peled Arnon Nagler

Purpose:Chemokine axis CXCR4/CXCL12 is critically involved in the survival and trafficking of normal andmalignant B lymphocytes.Here,we investigated the effect of high-affinityCXCR4antagonist BKT140on lymphoma cell growth and rituximab-induced cytotoxicity in vitro and in vivo. Experimental Design: In vitro efficacy of BKT140 alone or in combination with rituximab was determined in non-Hodgkin ...

Journal: :Hematological Oncology 2021

Allogeneic hematopoietic cell transplantation (alloHCT) used to play a defined role in the treatment of non-Hodgkin lymphoma (NHL). With advent modern targeted molecular therapies and immunotherapies, standards at least for B-cell have undergone significant changes, thereby questioning traditional alloHCT these diseases. This paper attempts describe current place perspectives rapidly evolving l...

Journal: :JPMA. The Journal of the Pakistan Medical Association 2000
S H Shah S Muzaffar S Pervez S H Hassan

OBJECTIVE To observe the frequency of histological subtypes of childhood non-Hodgkin's lymphoma and its immunohistochemical profile. SETTING All cases of non-Hodgkin's lymphoma diagnosed in children (< 15 years) in the section of histopathology at the Aga Khan University Hospital Karachi during the period of three years. METHODS These consecutive cases were evaluated on H&E stained sections...

Ali Akbar MovassaghPour Amir Monfaredan Azim Rezamand Hajar Nasiri, Heydar Ali Esmaeili Leyla Sahebi Majid Farshdousti Hagh Naser Mobarra, Nasser Rahimifar Safar Farajnia,

  Objective(s): Non- Hodgkin lymphoma (NHL) and acute lymphoblastic leukemia (ALL) are two main hematological malignances which have been driven from lymphoid tissue. Genetic polymorphisms in tumor necrosis factor-α (TNF-α) -308 and lymphotoxin-α (LT-α) +252 may affect their transcription and expression which leads to their high plasma level. The frequency of the TNF-α (-308) and LT-...

Journal: :Clinical cancer research : an official journal of the American Association for Cancer Research 2013
Katia Beider Elena Ribakovsky Michal Abraham Hanna Wald Lola Weiss Evgenia Rosenberg Eithan Galun Abraham Avigdor Orly Eizenberg Amnon Peled Arnon Nagler

PURPOSE Chemokine axis CXCR4/CXCL12 is critically involved in the survival and trafficking of normal and malignant B lymphocytes. Here, we investigated the effect of high-affinity CXCR4 antagonist BKT140 on lymphoma cell growth and rituximab-induced cytotoxicity in vitro and in vivo. EXPERIMENTAL DESIGN In vitro efficacy of BKT140 alone or in combination with rituximab was determined in non-H...

Journal: :Annals of oncology : official journal of the European Society for Medical Oncology 2013
A Trebouet T Marchand R Lemal E Gyan F Broussais-Guillaumot Y Guillermin H Monjanel G Salles S Le Gouill P Godmer C Fruchart G Damaj P Feugier C Thieblemont M Maynadié A Monnereau X Troussard D Rossille T Lamy R Houot

BACKGROUND Lymphoma occurring in patients aged 90 or older is not uncommon, and its incidence is expected to increase over time. Management of these patients is difficult given their underlying fragility and the lack of information regarding this population. PATIENTS AND METHODS We retrospectively analyzed 234 patients diagnosed with lymphoma at the age of 90 years or older (90+) between 1990...

Journal: :Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2008
Lesley A Anderson Ruth M Pfeiffer Joshua S Rapkin Gloria Gridley Lene Mellemkjaer Kari Hemminki Magnus Björkholm Neil E Caporaso Ola Landgren

PURPOSE Genetic factors are important in the etiology and pathogenesis of chronic lymphocytic leukemia (CLL), Hodgkin's lymphoma (HL), and non-Hodgkin's lymphoma (NHL). Only a few small studies have assessed clinical characteristics and prognosis for familial patients, with inconsistent findings. METHODS Using population-based registries from Sweden and Denmark, 7,749 patients with CLL, 7,476...

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