Since the BM7's last editorial on the topic' another 40 000 cases of bovine spongiform encephalopathy have been confirmed in cattle. New cases are being confirmed at the rate of 500 a week. Does it matter that between 1986 and 1989 we actually had the offal, which is now proscribed, going into the food chain?2 Several reasons are given for dismissing bovine spongiform encephalopathy as carrying...

1. Kitcharoen S, Pattapongsin M, Sawanyawisuth K, Angela V, Tiamkao S. Neurologic manifestations of pandemic (H1N1) 2009 virus infection. Emerg Infect Dis. 2010;16:569–70. DOI: 10.3201/ eid1603.091699 2. Kuiken T, Taubenberger JK. Pathology of human infl uenza revisited. Vaccine. 2008;26(Suppl 4):D59–66. DOI: 10.1016/j.vaccine.2008.07.025 3. Ito Y, Ichiyama T, Kimura H, Shibata M, Ishiwada N, K...

Mutations in human (Homo sapiens) ETHYLMALONIC ENCEPHALOPATHY PROTEIN1 (ETHE1) result in the complex metabolic disease ethylmalonic encephalopathy, which is characterized in part by brain lesions, lactic acidemia, excretion of ethylmalonic acid, and ultimately death. ETHE1-like genes are found in a wide range of organisms; however, the biochemical and physiological role(s) of ETHE1 have not bee...

The cardinal symptom of acute encephalopathy is impairment consciousness onset during the course an infectious disease, with duration and severity meeting defined criteria. Acute consists multiple syndromes such as necrotizing encephalopathy, biphasic seizures late reduced diffusion clinically mild encephalitis/encephalopathy reversible splenial lesion. Among these syndromes, there are both sim...

Diabetic encephalopathy may lead to cognitive deficits in diabetic patients and diminish quality of life. It has been shown that protracted hyperglycaemia is directly associated with neuronal apoptosis, which is involved in diabetic encephalopathy. The anaphase-promoting complex (APC) is essential for the survival of post-mitotic neurons. In our previous study, we found that the mitotic arrest ...

AIM To present the typical and atypical magnetic resonance (MR) imaging findings of alcoholic and non-alcoholic Wernicke's encephalopathy. METHODS This study included 7 patients with Wernicke's encephalopathy (2 men, 5 women; mean age, 52.3 years) that underwent brain MR examination between January 2012 and March 2016 in a single institution. Three patients were alcoholics and 4 patients were...

BACKGROUND & AIMS It remains unknown what the prevalence of minimal hepatic encephalopathy is in Taiwan, a highly endemic country for chronic viral hepatitis infection. It is also unclear whether abnormal serum cytokine levels can be indicative of the presence of minimal hepatic encephalopathy. We aimed to standardize the tests of psychometric hepatic encephalopathy score and predictive value o...

Background: The effects of magnesium physiology are contradictory to the neurotoxic effect of bilirubin, but the relationship between magnesium level and hyperbilirubinemia in neonates has not been well studied. In this study, we investigated the relationship between serum magnesium level and hyperbilirubinemia and hyperbilirubinemia complications at the Children’s Medical Center. Methods: In ...