AIM The aim of this study was to analyze relative citation ratio (RCR) of top twenty Macedonian biomedical scientists with a new metric that uses citation rates to measure influence at the article level. MATERIAL AND METHODS Top twenty Macedonian biomedical scientists were identified by GoPubMed on the base of the number of deposited abstracts in PubMed, corrected with the data from previousl...

The precise nick site in the double-strand origin (DSO) of pZMX201, a 1,668-bp rolling-circle replication (RCR) plasmid from the haloarchaeon Natrinema sp. CX2021, was determined by electron microscopy and DSO mapping. In this plasmid, DSO nicking occurred between residues C404 and G405 within a heptanucleotide sequence (TCTC/GGC) located in the stem region of an imperfect hairpin structure. Th...

In an effort to foster research integrity, the National Institutes of Health and the National Science Foundation mandate education of all trainees in the responsible conduct of research (RCR). Nevertheless, recent studies suggest that rates of questionable research practices and scientific misconduct are both high and considerably underreported. In part, this may be due to the fact that some et...

Requirements for educating the next generation of scientists in the responsible conduct of research (RCR) were published approximately 25 years ago. Over the years, an extensive collection of research ethics educational resources have been developed, most of which are available to the scientific community. We can use these resources to effect change in student learning about responsible and eth...

Training in the responsible conduct of research (RCR) is required for many research trainees nationwide, but little is known about its effectiveness. For a preliminary assessment of the effectiveness of a short-term course in RCR, medical students participating in an NIH-funded summer research program at the University of California, San Diego (UCSD) were surveyed using an instrument developed ...

The stream cipher TPypy has been designed by Biham and Seberry in January 2007 as the strongest member of the Py-family ciphers, after weaknesses in the other members Py, Pypy, Py6 were discovered. One main contribution of the paper is the detection of related-key weaknesses in the Py-family of ciphers including the strongest member TPypy. Under related keys, we show a distinguishing attack on ...

Detailed surface photometry has been carried out for three barred galaxies with use of high resolution CCD broadband images in the B, V and I bands. Using azimuthal luminosity profiles and their decomposition into Fourier Series, the structural parameters (length and strength) of the bars in the three galaxies have been obtained. We have also inferred the corotation radii (CR) using information...

Replication-competent retrovirus (RCR) vectors are intrinsically incapable of infecting quiescent cells and have been shown to achieve highly efficient and tumor-restricted replicative spread and gene transfer in vivo after direct intratumoral injection in a variety of primary cancer models. However, i.v. delivery of RCR vectors expressing therapeutic genes has never previously been tested, par...

Analytical models were developed and simulations of memory latency were performed for Uniform Memory Access (UMA), Non-Uniform Memory Access (NUMA), Local-RemoteGlobal (LRG), and RCR architectures for hit rates from 0.1 to 0.9 in steps of 0.1, memory access times of 10 to 100 ns, proportions of read/write access from 0.01 to 0.1, and block sizes of 8 to 64 words. The RCR architecture provides f...